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Study Title and Description

Association between low bone mass and calcium and caffeine intake among perimenopausal women in Southern Brazil: cross-sectional study.



Key Questions Addressed
1 For [population], is caffeine intake above [exposure dose], compared to intakes [exposure dose] or less, associated with adverse effects on bone and calcium balance outcomes?
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Primary Publication Information
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TitleData
Title Association between low bone mass and calcium and caffeine intake among perimenopausal women in Southern Brazil: cross-sectional study.
Author DL Harter,FM Busnello,RP Dibi,AT Stein,SK Kato,CM Vanin,
Country
Year 2013
Numbers

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Bone & Calcium Outcomes
Design Details
Question... Follow Up Answer Follow-up Answer
Refid 24310800
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What outcome is being evaluated in this paper? Bone and Calcium
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What is the objective of the study (as reported by the authors)? To evaluate the association between bone mass and calcium and caffeine intake among perimenopausal women in Southern Brazil.
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Provide a general description of the methods as reported by the authors. Information should be extracted based on relevance to the SR (i.e., caffeine related methods) Population: Women 40 years of age or older selected from the Air Force Hospital of Canoas and at the Municipal Cleansing Department of Porto Alegre in the cities of Porto Alegre and Canoas, Rio Grande do Sul, Brazil between March and May 2010. Current study part of a bigger study aimed at identifying the risk factors for osteoporosis and low bone mass. Nutritional profile based on measurements of weight, height, abdominal circumference, and tricipital skinfold. BMI and arm muscle circumference calculated. Calcium and caffeine intake based on validated semi-quantitative food frequency questionnaire (FFQ). Information regarding consumption of roasted and ground coffee, instant coffee, black tea, hot chocolate, chocolate in bars, soft drinks and chimarrão (yerba mate tea). The following responses were used: never, less than once a month, one to three times per month, once a week, two to four times per week, once a day and two or more times per day. The quantities considered for calculating nutrient intakes (mg/day) were obtained from food composition tables, and from the nutritional information on food packages when these foods were not included in the tables. Menopausal status based on self-reported questionnaires. Bone Mass: The estimated sample size for screening low bone mass using calcaneal ultrasound was 157 subjects, sampled consecutively. Low bone mass (LBM) screening was conducted using calcaneal quantitative ultrasound (QUS). Bone mineral density (BMD) from densitometry and QUS were used as predictors for any type of fracture and for osteoporotic fractures, regardless of BMD. Results were classified as losses of standard deviations (SD) in relation to normal young adult controls Statistical analysis: Comparison of calcium and caffeine consumptions in relation to bone mass classification was done using the non-parametric Mann-Whitney test. In all analyses, the significance level of 5% (P ≤ 0.05) was accepted.
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How many outcome-specific endpoints are evaluated? 1
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What is the (or one of the) endpoint(s) evaluated? (Each endpoint listed separately) Bone mass
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Clinical, physiological, other Clinical
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What is the study design? Cross-sectional
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Randomized or Non-Randomized?
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What were the diagnostics or methods used to measure the outcome? Objective
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Optional: Name of Method or short description calcaneal quantitative ultrasound (QUS)
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Caffeine (general)
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Coffee, Chocolate, energy drink, gum, medicine/supplement, soda, tea, other? coffee, chocolate, soda, tea
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Measured or self reported? Self-report
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Children, adolescents, adults, or pregnant included? Adults
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What was the reference, comparison, or control group(s)? (e.g. high vs low consumption, number of cups, etc.) Caffeine consumption in women with normal bone mass vs. low bone mass
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What were the listed confounders or modifying factors as stated by the authors? (e.g. multi-variable components of models.  Copy from methods) None evaluated.
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What were the sources of funding? Sources of funding: none
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What conflicts of interest were reported? Conflict of interest: none
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Results & Comparisons

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