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Study Title and Description

Effects of acute supplementation of caffeine on cardiorespiratory responses during endurance running in a hot & humid climate.



Key Questions Addressed
1 For [population], is caffeine intake above [exposure dose], compared to intakes [exposure dose] or less, associated with adverse effects on cardiovascular outcomes?
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Primary Publication Information
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TitleData
Title Effects of acute supplementation of caffeine on cardiorespiratory responses during endurance running in a hot & humid climate.
Author WC Ping,CC Keong,A Bandyopadhyay,
Country
Year 2010
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Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Cardiovascular Design
Design Details
Question... Follow Up Answer Follow-up Answer
What outcome is being evaluated in this paper? Cardiovascular
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What is the objective of the study (as reported by the authors)? The present study was conducted to find out the effect of acute supplementation of caffeine on cardiorespiratory responses during endurance running of male recreational runners in a hot and humid environment.
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Provide a general description of the methods as reported by the authors. Information should be extracted based on relevance to the SR (i.e., caffeine related methods) Selection of subjects: Nine (9) male Malaysian recreational runners (aged: 25.4 +/- 6.9 yr) were recruited in this randomized double-blind, placebo-controlled cross-over study. The study was conducted at the Sprots Science Unit Laboratory, Universiti Sains Malaysia, Kelantan, Malaysia. All the subjects were categorized as nonusers of caffeine (23.7 +/- 12.6 mg/day). Subjects with hypertension, asthma, diabetes, bronchitis, anaemia, heart problems, kidney or liver diseases and or any other major diseases were excluded from the study. Written informed consent was taken from each subject. Test procedure: Pre-trial and trial procedure - Each subject came to the laboratory five times, first 3 visits for pre-trial tests and remaining 2 visits for experimental trials, respectively (Fig.). First pre-trial visit involved the measurement of oxygen consumption at various submaximal running speeds while the second pre-trial visit involved the measurement of VO2max. These two trials were conducted to determine the exact treadmill speed that corresponded to the 70 per cent of the subject’s VO2max which was set as the exercise trial speed. Subjects were familiarized with the endurance testing protocol in the heat (310C, 70% relative humidity) on their third pre-trial visit. At least 3 days gap was maintained between the consecutive trials. For the experimental trials, each subject visited the laboratory twice with at least seven days gap to nullify the effect of the supplement, i.e., caffeine. Subjects reported to the laboratory after an overnight fast of 10 h. All the experimental trials were conducted at 0800 h. Measurement of oxygen uptake at submaximal running speeds - After the warm up, subject was asked to wear a mouthpiece, a nose clip and heart rate sensor (Sport Tester PE3000, Polar, Finland). Heart rate and rate of perceived exertion (RPE) were measured during the final min of each 4 min of the speed increment. Experimental trial protocol: On arrival to laboratory - Subject’s body weight (after emptying their bladder), body height, and preexercise heart rate were measured. A heart rate monitor (Sport Tester PE3000, Polar, Finland) was placed on the subject’s chest to monitor the heart rate. During the trials - Heart rate, core body temperature, room temperature, relative humidity and rate of perceived exertion or RPE were monitored at intervals of 10 min.
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How many outcome-specific endpoints are evaluated? 1
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What is the (or one of the) endpoint(s) evaluated? (Each endpoint listed separately) Heart rate
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List additional health endpoints (separately). 2
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List additional health endpoints (separately).3
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List additional health endpoints (separately).4
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List additional health endpoints (separately).5
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List additional health endpoints (separately).6
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Clinical, physiological, other Physiological
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What is the study design? Controlled Trial
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Randomized or Non-Randomized? RCT
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What were the diagnostics or methods used to measure the outcome? Objective
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Optional: Name of Method or short description A heart rate monitor (Sport Tester PE3000, Polar, Finland) was placed on the subject’s chest to monitor the heart rate.
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Caffeine (general) Caffeine (general)
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Coffee, Chocolate, energy drink, gum, medicine/supplement, soda, tea, other?
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Measured or self reported? Measured
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Children, adolescents, adults, or pregnant included? Adults
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What was the reference, comparison, or control group(s)? (e.g. high vs low consumption, number of cups, etc.) Placebo; baseline measurements of heart rate also recorded.
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What were the listed confounders or modifying factors as stated by the authors? (e.g. multi-variable components of models.  Copy from methods) Subjects with hypertension, asthma, diabetes, bronchitis, anaemia, heart problems, kidney or liver diseases and or any other major diseases were excluded from the study.
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What conflicts of interest were reported? Not discussed.
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Refid 20693587
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What were the sources of funding? The financial assistance provided by the Universiti Sains Malaysia (vide short term grant no. 304/PPSP/6131556) is acknowledged.
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Results & Comparisons

No Results found.