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Study Title and Description

Effect of eucaloric high- and low-sucrose diets with identical macronutrient profile on insulin resistance and vascular risk: a randomized controlled trial.



Key Questions Addressed
1 What is the effect of sugars on health outcomes in intervention studies?
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Primary Publication Information
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TitleData
Title Effect of eucaloric high- and low-sucrose diets with identical macronutrient profile on insulin resistance and vascular risk: a randomized controlled trial.
Author Black RN., Spence M., McMahon RO., Cuskelly GJ., Ennis CN., McCance DR., Young IS., Bell PM., Hunter SJ.
Country Regional Centre for Endocrinology and Diabetes, Royal Victoria Hospital, Grosvenor Road, Belfast, U.K.
Year 2006
Numbers Pubmed ID: 17130505
652785 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Sugar Evidence Map Intervention Studies
Arms
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Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Randomized Controlled Trial (crossover)
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Trial Name nr
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Funding Source Grant from Sugar Bureau and Suikerstichting; R&D fellowship from the Northern Ireland Department of Health and Social Services Research and Development Office
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Intervention (Exposure) Information Sucrose
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25% sucrose diet from both solid and liquid food items
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25% of total diet energy (13.4mJ)
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6 weeks
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Replacement
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Study Randomization Yes
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Yes
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Yes
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Was there a washout period between interventions? ... Length of Washout Yes ... 4 weeks
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Comparator Information Sucrose
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10% diet (13.3mJ)
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Isocaloric
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Baseline Health Status healthy
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Sample Size 13
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Anthropometry at Baseline ... Measure BMI ... 26.6 (0.9)
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Body Weight 86.0 (3.4)
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kg/m2 (SD)
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26.6 (0.9)
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Male % 100
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Country United Kingdom
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Age ... Value Mean ... 33
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Standard Deviation ... 3
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Was a power calculation performed? Yes
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Was the study blinded? No
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What is the study population? Adults
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Publication Year 2006
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