Study Preview
Study Title and Description
Children with NAFLD are more sensitive to the adverse metabolic effects of fructose beverages than children without NAFLD.
Key Questions Addressed
1 | What is the effect of sugars on health outcomes in intervention studies? |
Primary Publication Information
Title | Children with NAFLD are more sensitive to the adverse metabolic effects of fructose beverages than children without NAFLD. |
Author | Jin R., Le NA., Liu S., Farkas Epperson M., Ziegler TR., Welsh JA., Jones DP., McClain CJ., Vos MB. |
Country | Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA. |
Year | 2012 |
Numbers |
Pubmed ID: 22544914 20043463 (internal) |
Secondary Publication Information
There are currently no secondary publications defined for this study.
Extraction Form: Sugar Evidence Map Intervention Studies
Arms
Number | Title | Description | Comments |
---|---|---|---|
1 | Fructose | ||
2 | Glucose |
Question... Follow Up | Answer | Follow-up Answer | |
---|---|---|---|
Study Design | Randomized Controlled Trial (crossover) | ||
Trial Name | nr | ||
Funding Source | Obesity Society Award; NIH grants | ||
Intervention (Exposure) Information | Fructose | ||
granulated fructose dissolved in water | |||
nr | |||
one visit. in ward for 2 days | |||
Supplement | |||
Study Randomization | No | ||
Yes | |||
Was there a washout period between interventions? ... Length of Washout | Yes ... | 5-14 days | |
Comparator Information | glucose as dextrose in water | ||
nd | |||
Isocaloric | |||
Baseline Health Status | half healthy half with NAFLD | ||
Sample Size | 19 | ||
Anthropometry at Baseline | Non-NAFLD, NAFLD (SE) | ||
1.0 (0.3), 2.2 (0.1) | |||
Male % | 89 | ||
Country | United States | ||
Age ... Value | Mean ... | Non-NAFLD=13.8; NAFLD=13.6 | |
Standard Error ... | Non-NAFLD=0.7; NAFLD=0.9 | ||
Was a power calculation performed? | Yes | ||
Was the study blinded? | Yes | ||
Yes | |||
No | |||
Yes | |||
What is the study population? | Children | ||
Publication Year | 2012 |
Results & Comparisons
No Results found.