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Study Title and Description

Endocrine and metabolic effects of consuming fructose- and glucose-sweetened beverages with meals in obese men and women: influence of insulin resistance on plasma triglyceride responses.



Key Questions Addressed
1 What is the effect of sugars on health outcomes in intervention studies?
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Primary Publication Information
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TitleData
Title Endocrine and metabolic effects of consuming fructose- and glucose-sweetened beverages with meals in obese men and women: influence of insulin resistance on plasma triglyceride responses.
Author Teff KL., Grudziak J., Townsend RR., Dunn TN., Grant RW., Adams SH., Keim NL., Cummings BP., Stanhope KL., Havel PJ.
Country Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104, USA. kteff@pobox.upenn.edu
Year 2009
Numbers Pubmed ID: 19208729
20034369 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Sugar Evidence Map Intervention Studies
Arms
Number Title Description Comments
1 Fructose
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2 Glucose
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Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Randomized Controlled Trial (crossover)
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Trial Name nr
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Funding Source grants from Univ of Penn, NIH, ADA, USDA
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Intervention (Exposure) Information Fructose
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in beverages
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30% of calories
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2 day
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Replacement
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Study Randomization No
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Was there a washout period between interventions? ... Length of Washout Yes ... 1 month
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Comparator Information glucose
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30% of calories
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Isocaloric
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Baseline Health Status obese
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Sample Size 17
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Anthropometry at Baseline mean
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34.6
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Male % 53
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Country USA
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Age ... Value Mean ... 33
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Was a power calculation performed? No
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Was the study blinded? Unclear
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What is the study population? Adults
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Publication Year 2009
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Results & Comparisons


Results Data
N Enrolled Mean Difference Standard Deviation P-Value
Outcome: Glucose (blood sugar)      Population: All Participants Between-Arm Comparisons
Time Point Measure Fructose Glucose Comparison Measure ERROR vs. ERROR


2 days

N Analyzed
Mean
Standard Deviation
N Enrolled Mean Difference Standard Deviation P-Value
Outcome: Glucose (blood sugar)      Population: males Between-Arm Comparisons
Time Point Measure Fructose Glucose Comparison Measure Fructose vs. Glucose


2 days

N Analyzed 9 9
Mean 429.1 228.4
Standard Error 45.7 35.9