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Study Title and Description

Comparative effects of fructose, aspartame, glucose, and water preloads on calorie and macronutrient intake.



Key Questions Addressed
1 What is the effect of sugars on health outcomes in intervention studies?
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Primary Publication Information
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TitleData
Title Comparative effects of fructose, aspartame, glucose, and water preloads on calorie and macronutrient intake.
Author Rodin J.
Country Department of Psychology, Yale University, New Haven, CT 06520.
Year 1990
Numbers Pubmed ID: 2178391
2014_16335 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Sugar Evidence Map Intervention Studies
Arms
Number Title Description Comments
1 Fructose 50 g in 500 mL of deionized, distilled, lemon-flavored water
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2 Glucose 50 g in 500 mL of deionized, distilled, lemon-flavored water
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3 aspartame .25 g in 500 mL of deionized, distilled, lemon-flavored water
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4 water 500 mL of unflavored, unsweetened water
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Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Randomized Controlled Trial (crossover)
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Trial Name nr
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Funding Source NIH grant, Division of Research Resources, to the Clinical Research Center and by a grant from Xyrofin-Finnsugar.
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Intervention (Exposure) Information Fructose
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Glucose
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aspartame
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50g of fructose in 500 ml deionized, distilled lemon-flavored water
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50g of glucose in 500 ml deionized, distilled lemon-flavored water
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.25g of aspartame in 500 ml deionized, distilled lemon-flavored water
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50g
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50g
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.25g
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10 min
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10 min
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10 min
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Replacement
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Replacement
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Replacement
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Study Randomization Yes
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No
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Was there a washout period between interventions? ... Length of Washout Yes ... 1 week
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Comparator Information Water
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500 mL of unflavored, unsweetened
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Hypercaloric
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Baseline Health Status Normal weight and overweight
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Sample Size 20
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Anthropometry at Baseline nr
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nr
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Male % 50
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Country USA
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Age ... Value Range ... 22-50
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Was a power calculation performed? No
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Was the study blinded? Unclear
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What is the study population? Adults
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Publication Year 1990
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Results & Comparisons

No Results found.