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Study Title and Description

Effects of high-fructose corn syrup and sucrose on the pharmacokinetics of fructose and acute metabolic and hemodynamic responses in healthy subjects.



Key Questions Addressed
1 What is the effect of sugars on health outcomes in intervention studies?
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Primary Publication Information
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TitleData
Title Effects of high-fructose corn syrup and sucrose on the pharmacokinetics of fructose and acute metabolic and hemodynamic responses in healthy subjects.
Author Le MT., Frye RF., Rivard CJ., Cheng J., McFann KK., Segal MS., Johnson RJ., Johnson JA.
Country Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL 32610, USA.
Year 2012
Numbers Pubmed ID: 22152650
4125 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Sugar Evidence Map Intervention Studies
Arms
Number Title Description Comments
1 HFCS
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2 Sucrose
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Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Randomized Controlled Trial (crossover)
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Trial Name nr
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Funding Source supported by the Center for Pharmacogenomics and the CTSI at University of Florida, and National Institutes of Health training grant
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Intervention (Exposure) Information High Fructose Corn Syrup/Corn Syrup
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Sucrose
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in a soft drink
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in a soft drink
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68g sugar
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69.4g sugar
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6 hours
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6 hours
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Replacement
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Replacement
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Study Randomization Yes
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Was there a washout period between interventions? ... Length of Washout Yes ... 2 days
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Baseline Health Status healthy
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Sample Size 40
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Anthropometry at Baseline mean
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25.9
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Male % 40
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Country USA
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Age ... Value Mean ... 27.1
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Was a power calculation performed? Yes
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Was the study blinded? Yes
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Yes
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No
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No
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What is the study population? Adults
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Publication Year 2012
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Results & Comparisons

No Results found.