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Study Title and Description

A dual sugar challenge test for lipogenic sensitivity to dietary fructose.



Key Questions Addressed
1 What is the effect of sugars on health outcomes in intervention studies?
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Primary Publication Information
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TitleData
Title A dual sugar challenge test for lipogenic sensitivity to dietary fructose.
Author Hudgins LC., Parker TS., Levine DM., Hellerstein MK.
Country The Rogosin Institute, New York, New York 10065, USA. lih2013@nyp.org
Year 2011
Numbers Pubmed ID: 21252253

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Sugar Evidence Map Intervention Studies
Arms
Number Title Description Comments
1 Fructose Protocol 1: 1.4 g/kg dissolved in 360 ml water and divided into 13 doses (each 1 ounce) every half hour between 0800 and 1400 h. The average total dose of fructose was 108 g or 432 kcal.
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2 Fructose Proctol 2: fructose (0.5 g/kg) dissolved in 12 ounces of water and consumed in 15 min
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3 Glucose + Fructose Protocol 2: fructose (0.5 g/kg)  glucose (0.5 g/kg) dissolved in 12 ounces of water and consumed in 15 min
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4 Glucose + Fructose 2x Protocol 2: fructose (1 g/kg) + glucose (1 g/kg) dissolved in 12 ounces of water and consumed in 15 min
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Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Randomized Controlled Trial (crossover)
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Trial Name nr
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Funding Source General Clinical Research Center grant; a Clinical Center for Translational Science award from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH) and NIH Roadmap for Medical Research; The Robert C. Atkins Foundation; funds from William and Linda Macaulay; and an award from the College of Natural Resources, University of California at Berkeley, California.
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Intervention (Exposure) Information Fructose
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Fructose + glucose
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fructose + glucose
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Fructose
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dissolved in 12 ounces of water and consumed in 15 min
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dissolved in 12 ounces of water and consumed in 15 min
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dissolved in 12 ounces of water and consumed in 15 min
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dissolved in 360 ml water and divided into 13 doses (each 1 ounce) every half hour between 0800 and 1400 h
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0.5 g/kg
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0.5 g/kg each
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1 g/kg each
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108 g total
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1 time
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1 time
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1 time
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6 hours
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Replacement
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Replacement
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Replacement
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Replacement
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Study Randomization Yes
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Yes
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Was there a washout period between interventions? Not Reported
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Baseline Health Status healthy lean, overweight
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Sample Size 15
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Anthropometry at Baseline mean
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26.2
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Male % 60
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Country USA
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Age ... Value Mean ... 32
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Was a power calculation performed? No
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Was the study blinded? No
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No
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No
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No
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What is the study population? Adults
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Publication Year 2011
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Results & Comparisons

No Results found.