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Study Title and Description

Effects of probiotic or prebiotic supplemented milk formulas on fecal microbiota composition of infants.



Key Questions Addressed
1 Is this an intervention study?
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Primary Publication Information
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TitleData
Title Effects of probiotic or prebiotic supplemented milk formulas on fecal microbiota composition of infants.
Author Brunser O., Figueroa G., Gotteland M., Haschke-Becher E., Magliola C., Rochat F., Cruchet S., Palframan R., Gibson G., Chauffard F., Haschke F.
Country Ultrastructure Laboratory, Institute of Nutrition and Food Technology (INTA),University of Chile, J.P. Alessandri 5540, Santiago, Chile. obrunser@inta.cl
Year 2006
Numbers Pubmed ID: 16837430

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Fiber 4.1
Arms
No arms have been defined in this extraction form.

Design Details
Question... Follow Up Answer Follow-up Answer
pubyear 2006
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country Chile
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design Randomized Controlled Trial (parallel)
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blindness Double blind
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diet Isocaloric/Maintenance
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feedcontrol Food partially provided (partial metabolic study)
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sampsize 116 (90 were randomized upfront, 26 breastfed added later)
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runin No
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washout Not applicable
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dosechange No
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age_adult
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age_adol
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age_child
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age_baby
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age_infant 1
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age_oth
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age_mean NR
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age_range NR
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bmi_mean NR
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bmi_range NR
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blhealth_healthy 1
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blhealth_hyperlip
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blhealth_diab
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blhealth_hyperten
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blhealth_digest
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blhealth_met
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blhealth_oth
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blhealth_othspec
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gender breastfed group ~93%, standard formula ~93.6%, probiotic group ~93.8%, prebiotic group 93.4%
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ftype1 Fructooligosaccharide
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descrip1_1
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descrip1_2
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dose1_1 FOS at a concentration of 2 grams per liter of prepared formula
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dose1_2
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duration1 13 weeks total, 7 weeks on study diet
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admin1 Beverage
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ftype2
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descrip2_1
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descrip2_2
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dose2_1
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dose2_2
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duration2
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admin2
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ftype3
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descrip3_1
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descrip3_2
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dose3_1
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dose3_2
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duration3
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admin3
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ftype4
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descrip4_1
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descrip4_2
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dose4_1
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dose4_2
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duration4
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admin4
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comparator1 breastmilk
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cdose1 NR
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cduration1 13 weeks total, 7 weeks on study diet
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cadmin1 Beverage
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comparator2 standard infant formula
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cdose2 NR
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cduration2 13 weeks total, 7 weeks on study diet
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cadmin2 Beverage
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comparator3 standard infant formula + probiotic (Lactobacillus johnsonii La1)
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cdose3 1.8x10^8 La1 per day
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cduration3 13 weeks total, 7 weeks on study diet
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cadmin3 Beverage
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comparator4
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cdose4
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cduration4
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cadmin4
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Baseline Characteristics
No baseline characteristics have been defined for this extraction form.



Results & Comparisons

No Results found.
Adverse Events
Arm or Total Title Description Comments

Quality Dimensions
No quality dimensions were specified.

Quality Rating
No quality rating data was found.