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Study Title and Description

Diets high in resistant starch increase plasma levels of trimethylamine-N-oxide, a gut microbiome metabolite associated with CVD risk.



Key Questions Addressed
1 Is this an intervention study?
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Primary Publication Information
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TitleData
Title Diets high in resistant starch increase plasma levels of trimethylamine-N-oxide, a gut microbiome metabolite associated with CVD risk.
Author Bergeron N., Williams PT., Lamendella R., Faghihnia N., Grube A., Li X., Wang Z., Knight R., Jansson JK., Hazen SL., Krauss RM.
Country 1Children's Hospital Oakland Research Institute,Oakland,CA 94609,USA.
Year 2016
Numbers Pubmed ID: 27993177

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Fiber 4.1
Arms
No arms have been defined in this extraction form.

Design Details
Question... Follow Up Answer Follow-up Answer
pubyear 2017
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country United States
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design Randomized Controlled Trial (Crossover)
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blindness Double blind
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diet Isocaloric/Maintenance
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feedcontrol All food provided (metabolic study)
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sampsize 52
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runin No
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washout Yes
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dosechange No
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age_adult 1
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age_adol
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age_child
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age_baby
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age_infant
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age_oth
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age_mean 44
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age_range men >20 women >=43
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bmi_mean 31
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bmi_range 20-35
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blhealth_healthy 1
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blhealth_hyperlip
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blhealth_diab
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blhealth_hyperten
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blhealth_digest
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blhealth_met
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blhealth_oth
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blhealth_othspec
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gender ~38
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ftype1 Corn starch/cornflour/maize starch
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descrip1_1
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descrip1_2
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dose1_1 19-26
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dose1_2
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duration1 2 weeks
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admin1 Combination beverage + foods
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ftype2
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descrip2_1
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descrip2_2
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dose2_1
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dose2_2
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duration2
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admin2
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ftype3
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descrip3_1
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descrip3_2
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dose3_1
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dose3_2
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duration3
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admin3
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ftype4
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descrip4_1
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descrip4_2
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dose4_1
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dose4_2
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duration4
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admin4
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comparator1 low-RS
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cdose1 3-4
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cduration1 2 weeks
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cadmin1 Combination beverage + foods
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comparator2
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cdose2
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cduration2
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cadmin2
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comparator3
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cdose3
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cduration3
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cadmin3
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comparator4
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cdose4
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cduration4
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cadmin4
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Baseline Characteristics
No baseline characteristics have been defined for this extraction form.



Results & Comparisons

No Results found.
Adverse Events
Arm or Total Title Description Comments

Quality Dimensions
No quality dimensions were specified.

Quality Rating
No quality rating data was found.