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Study Title and Description

Prebiotic galacto-oligosaccharides mitigate the adverse effects of iron fortification on the gut microbiome: a randomised controlled study in Kenyan infants.



Key Questions Addressed
1 Is this an intervention study?
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Primary Publication Information
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TitleData
Title Prebiotic galacto-oligosaccharides mitigate the adverse effects of iron fortification on the gut microbiome: a randomised controlled study in Kenyan infants.
Author Paganini D., Uyoga MA., Kortman GAM., Cercamondi CI., Moretti D., Barth-Jaeggi T., Schwab C., Boekhorst J., Timmerman HM., Lacroix C., Karanja S., Zimmermann MB.
Country Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
Year 2017
Numbers Pubmed ID: 28774885

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Fiber 4.1
Arms
No arms have been defined in this extraction form.

Design Details
Question... Follow Up Answer Follow-up Answer
pubyear 2017
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country Kenya
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design Randomized Controlled Trial (parallel)
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blindness Single blind
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diet Isocaloric/Maintenance
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feedcontrol Food partially provided (partial metabolic study)
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sampsize 155
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runin Yes
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washout Not applicable
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dosechange No
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age_adult
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age_adol
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age_child
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age_baby
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age_infant 1
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age_oth
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age_mean NR
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age_range 6.5-9.5 months
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bmi_mean NR
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bmi_range NR
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blhealth_healthy 1
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blhealth_hyperlip
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blhealth_diab
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blhealth_hyperten
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blhealth_digest
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blhealth_met
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blhealth_oth
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blhealth_othspec
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gender ~50
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ftype1 Galactooligosaccharide
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descrip1_1
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descrip1_2
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dose1_1 ~7.5 (10.5 g 75% GOS)
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dose1_2
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duration1 4 months
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admin1 Powder
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ftype2
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descrip2_1
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descrip2_2
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dose2_1
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dose2_2
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duration2
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admin2
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ftype3
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descrip3_1
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descrip3_2
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dose3_1
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dose3_2
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duration3
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admin3
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ftype4
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descrip4_1
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descrip4_2
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dose4_1
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dose4_2
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duration4
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admin4
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comparator1 maltodextrin
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cdose1 10.5
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cduration1 4 months
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cadmin1 Powder
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comparator2 maltodextrin +NaFeEDTA+ferrous fumarate
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cdose2 10.5 g maltodextrin, 2.5mg NaFeEDTA, 2.5 mg ferrous fumarate
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cduration2 4 months
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cadmin2 Powder
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comparator3
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cdose3
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cduration3
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cadmin3
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comparator4
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cdose4
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cduration4
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cadmin4
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Baseline Characteristics
No baseline characteristics have been defined for this extraction form.



Results & Comparisons

No Results found.
Adverse Events
Arm or Total Title Description Comments

Quality Dimensions
No quality dimensions were specified.

Quality Rating
No quality rating data was found.