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Project: Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults

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Project Summary

Title and Description


Key Questions


Associated Extraction Forms

Title Created by Key Questions Addressed Form Notes
Extraction Form Diana Sobieraj 1, 2


Associated Studies (each link opens a new tab)

Title Author Year
A double-blind study of paroxetine compared with fluoxetine in geriatric patients with major depression. Schöne W., Ludwig M. 1993
Escitalopram in the treatment of depressed elderly patients. Kasper S., de Swart H., Friis Andersen H. 2005
Paroxetine and fluoxetine effects on mood and cognitive functions in depressed nondemented elderly patients. Cassano GB., Puca F., Scapicchio PL., Trabucchi M. 2002
A double-blind, placebo-controlled study of venlafaxine and fluoxetine in geriatric outpatients with major depression. Schatzberg A., Roose S. 2006
Evaluation of two-dimensional gas chromatography-time-of-flight mass spectrometry for the determination of multiple pesticide residues in fruit. Zrostlíková J., Hajslová J., Cajka T. 2003
Escitalopram prevents relapse in older patients with major depressive disorder. Gorwood P., Weiller E., Lemming O., Katona C. 2007
Efficacy of citalopram in the prevention of recurrent depression in elderly patients: placebo-controlled study of maintenance therapy. Klysner R., Bent-Hansen J., Hansen HL., Lunde M., Pleidrup E., Poulsen DL., Andersen M., Petersen HE. 2002
Antidepressant pharmacotherapy in the treatment of depression in the very old: a randomized, placebo-controlled trial. Roose SP., Sackeim HA., Krishnan KR., Pollock BG., Alexopoulos G., Lavretsky H., Katz IR., Hakkarainen H. 2004
A double-blind, placebo-controlled treatment trial of citalopram for major depressive disorder in older patients with heart failure: the relevance of the placebo effect and psychological symptoms. Fraguas R., da Silva Telles RM., Alves TC., Andrei AM., Rays J., Iosifescu DV., Wajngarten M. 2009
Comparative efficacy and safety of sertraline versus nortriptyline in major depression in patients 70 and older. Finkel SI., Richter EM., Clary CM. 1999
Comparison of the tolerability and efficacy of citalopram and amitriptyline in elderly depressed patients treated in general practice. Kyle CJ., Petersen HE., Overø KF. 1998
Paroxetine in the treatment of elderly depressed patients in general practice: a double-blind comparison with amitriptyline. Hutchinson DR., Tong S., Moon CA., Vince M., Clarke A. 1992
Safety and tolerability of duloxetine at 60 mg once daily in elderly patients with major depressive disorder. Raskin J., Wiltse CG., Dinkel JJ., Walker DJ., Desaiah D., Katona C. 2008
Efficacy and tolerability of venlafaxine in geriatric outpatients with major depression: a double-blind, randomised 6-month comparative trial with citalopram. Allard P., Gram L., Timdahl K., Behnke K., Hanson M., Søgaard J. 2004
Comparative efficacy of sertraline vs. fluoxetine in patients age 70 or over with major depression. Finkel SI., Richter EM., Clary CM., Batzar E. 1999
Double-blind, randomized comparison of mirtazapine and paroxetine in elderly depressed patients. Schatzberg AF., Kremer C., Rodrigues HE., Murphy GM. -- Not Found --
Double-blind, placebo-controlled evaluation of extended-release bupropion in elderly patients with major depressive disorder. Hewett K., Chrzanowski W., Jokinen R., Felgentreff R., Shrivastava RK., Gee MD., Wightman DS., O'Leary MC., Millen LS., Leon MC., Briggs MA., Krishen A., Modell JG. 2010
Acute and long-term treatment of late-life major depressive disorder: duloxetine versus placebo. Robinson M., Oakes TM., Raskin J., Liu P., Shoemaker S., Nelson JC. 2014
A randomized, double-blind, placebo-controlled, duloxetine-referenced, fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with major depressive disorder. Katona C., Hansen T., Olsen CK. 2012
Antidepressant use and risk of adverse outcomes in older people: population based cohort study. Coupland C., Dhiman P., Morriss R., Arthur A., Barton G., Hippisley-Cox J. 2011
Comparison of treatment persistence, hospital utilization and costs among major depressive disorder geriatric patients treated with escitalopram versus other SSRI/SNRI antidepressants. Wu E., Greenberg P., Yang E., Yu A., Ben-Hamadi R., Erder MH. 2008




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