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Study Title and Description

Routine screening for colon cancer after conservative treatment of diverticulitis.



Key Questions Addressed
3 KQ 3: What are the benefits and harms of colonoscopy (or other colon imaging test) following an episode of acute diverticulitis? KQ 3a. What is the incidence of malignant and premalignant colon tumors found by colonoscopy, and what is the incidence of colon cancer mortality among patients undergoing screening? KQ 3b. What are the procedure-related and other harms of colonoscopy or CT colonography? KQ 3c. What is the frequency of inadequate imaging due to intolerance or technical feasibility? • Do the benefits and harms vary by patient characteristics, course of illness, or other factors?
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Primary Publication Information
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TitleData
Title Routine screening for colon cancer after conservative treatment of diverticulitis.
Author Schout PJ., Spillenaar Bilgen EJ., Groenen MJ.
Country Department of Surgery, Rijnstate Hospital Arnhem, Arnhem, The Netherlands.
Year 2012
Numbers Pubmed ID: 23171930

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: KQ 3: Colonoscopy
Arms
Number Title Description Comments
1 Colonoscopy
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Design Details
Question... Follow Up Answer Follow-up Answer
Study design Single group, no subgroup analysis
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if not an RCT, what was the directionality? Retrospective
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Funder Not reported (or unclear)
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Start and end years of the study 2000
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2010
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Inclusion criteria Patients who underwent radiological or surgical abscess drainage only without colon resection
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Exclusion criteria patients who underwent surgical treatment, had a history of colon cancer, had another underlying disease which caused an intra-abdominal abscess, or underwent colonoscopy in the diagnostic process of the episode of diverticulitis
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Specific population? No (anyone with Hx diverticulitis)
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Note/Comment about Design (or overall study)
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Country Netherlands
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Comparison of colonoscopy vs. no colonoscopy? No
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Comparison of diverticulitis vs health control? No
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Baseline Characteristics
Question Colonoscopy Total Comments
AnswerFollow-up AnswerFollow-up
Participant race/ethnicity characteristics Male NR Male NR
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Participant age, continuous No data entered.
Age >=50, % NR NR
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Participants with Un/Complicated Diverticulitis Not reported Not reported
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Note/Comment about baseline characteristics No data entered.
Alarm symptoms either rectal bleeding, significant weight loss or persistent abdominal pain or a combination of these
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6 out of 8 patients with a malignant tumor
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Results & Comparisons


Results Data
Outcome: Colorectal cancer      Population: All Participants
Time Point Measure Colonoscopy


Enter a numeric value or title (required) years

 N Analyzed 422
Counts 8
Percentage 1.9


Quality Dimensions
Dimension Value Notes Comments
Q23: NHLBI - Were eligibility/selection criteria for the study population prespecified and clearly described? Yes
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Q25: NHLBI - Were the outcome measures prespecified, clearly defined, valid, reliable, and assessed consistently across all study participants? Yes
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If this study was an NRCS or a single-group study, did the study report adjusted results that were for differences between groups (in the case of NRCSs) or differences between subgroups (in the case of single group studies)? No
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Quality Rating
No quality rating data was found.