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Study Title and Description

Underlying Colorectal Cancer Was Rarely Detected After an Episode of Acute Diverticulitis: a Retrospective Analysis of 225 Patients.



Key Questions Addressed
3 KQ 3: What are the benefits and harms of colonoscopy (or other colon imaging test) following an episode of acute diverticulitis? KQ 3a. What is the incidence of malignant and premalignant colon tumors found by colonoscopy, and what is the incidence of colon cancer mortality among patients undergoing screening? KQ 3b. What are the procedure-related and other harms of colonoscopy or CT colonography? KQ 3c. What is the frequency of inadequate imaging due to intolerance or technical feasibility? • Do the benefits and harms vary by patient characteristics, course of illness, or other factors?
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Primary Publication Information
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TitleData
Title Underlying Colorectal Cancer Was Rarely Detected After an Episode of Acute Diverticulitis: a Retrospective Analysis of 225 Patients.
Author Khoury T., Mahamid M., Lubany A., Safadi M., Farah A., Sbeit W., Mari A.
Country Gastroenterology and endoscopy united, The Nazareth Hospital, EMMS, Nazareth, Israel. tawfikkhoury1@hotmail.com.
Year 2019
Numbers Pubmed ID: 30632029

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: KQ 3: Colonoscopy
Arms
Number Title Description Comments
1 Colonoscopy
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Design Details
Question... Follow Up Answer Follow-up Answer
Study design Single group, no subgroup analysis
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Single group, no subgroup analysis
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if not an RCT, what was the directionality? Retrospective
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Funder Not reported (or unclear)
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Start and end years of the study 2014
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2018
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Inclusion criteria >16 years, acute diverticulitis, patients who underwent colonoscopy in the period of 6 months following the diagnosis with acute diverticulitis, or patients who performed virtual CT colonography in the case of contraindication to colonoscopy.
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Exclusion criteria Exclusion criteria included patients with undetermined diagnosis of acute diverticulitis; patient who did not complete colonoscopy in the scheduled time; history of inflammatory bowel conditions such as inflammatory bowel disease, collagenous colitis, microscopic colitis, and eosinophilic colitis; patients with oncological diseases; and patients with immunosuppressive therapy.
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Specific population? No (anyone with Hx diverticulitis)
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No (anyone with Hx diverticulitis)
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No (anyone with Hx diverticulitis)
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No (anyone with Hx diverticulitis)
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Note/Comment about Design (or overall study)
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Country Israel
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Comparison of colonoscopy vs. no colonoscopy? No
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Comparison of diverticulitis vs health control? No
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Baseline Characteristics
Question Colonoscopy Total Comments
AnswerFollow-up AnswerFollow-up
Participant race/ethnicity characteristics Male 62
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Participant age, continuous 55.73
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13.81
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24
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93
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Age >=50, % No data entered.
Participants with Un/Complicated Diverticulitis No data entered.
Note/Comment about baseline characteristics Location of Diverticulitis (total = 225) Right: 16 (7.1%) Left: 202 (89.7)
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Alarm symptoms No data entered.



Results & Comparisons


Results Data
Outcome: Colorectal cancer      Population: All Participants
Time Point Measure Colonoscopy


Enter a numeric value or title (required) years

 N Analyzed 225
Counts 17
Percentage 7.56


Quality Dimensions
Dimension Value Notes Comments
Q23: NHLBI - Were eligibility/selection criteria for the study population prespecified and clearly described? Yes
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Q25: NHLBI - Were the outcome measures prespecified, clearly defined, valid, reliable, and assessed consistently across all study participants? Yes
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If this study was an NRCS or a single-group study, did the study report adjusted results that were for differences between groups (in the case of NRCSs) or differences between subgroups (in the case of single group studies)? No
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Quality Rating
No quality rating data was found.