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Study Title and Description

Colonoscopy after the first episode of acute diverticulitis: challenging management paradigms.



Key Questions Addressed
3 KQ 3: What are the benefits and harms of colonoscopy (or other colon imaging test) following an episode of acute diverticulitis? KQ 3a. What is the incidence of malignant and premalignant colon tumors found by colonoscopy, and what is the incidence of colon cancer mortality among patients undergoing screening? KQ 3b. What are the procedure-related and other harms of colonoscopy or CT colonography? KQ 3c. What is the frequency of inadequate imaging due to intolerance or technical feasibility? • Do the benefits and harms vary by patient characteristics, course of illness, or other factors?
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Primary Publication Information
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TitleData
Title Colonoscopy after the first episode of acute diverticulitis: challenging management paradigms.
Author Horesh N., Saeed Y., Horesh H., Berger Y., Speter C., Pery R., Rosin D., Gutman M., Zmora O.
Country Department of Surgery and Transplantations B, Chaim Sheba Medical Center (Affiliated to the Faculty of Medicine, Tel Aviv University), 52621, Tel-Hashomer, Ramat Gan, Israel. nir_horesh@hotmail.com.
Year 2016
Numbers Pubmed ID: 27170283

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: KQ 3: Colonoscopy
Arms
Number Title Description Comments
1 Colonoscopy
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Design Details
Question... Follow Up Answer Follow-up Answer
Study design Single group, with subgroup analyses
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Single group, with subgroup analyses
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if not an RCT, what was the directionality? Retrospective
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Funder Not reported (or unclear)
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Start and end years of the study 2008
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2012
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Inclusion criteria patients admitted for a first episode of acute diverticulitis diagnosed based on clinical signs and CT findings and were successfully treated conservatively
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Exclusion criteria patients who underwent colonoscopy during the year prior to presentation
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Specific population? No (anyone with Hx diverticulitis)
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No (anyone with Hx diverticulitis)
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Note/Comment about Design (or overall study)
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Country Israel
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Comparison of colonoscopy vs. no colonoscopy? No
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Comparison of diverticulitis vs health control? No
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Subgroup analyses? Age <> 50
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Baseline Characteristics
Question Colonoscopy Total Comments
AnswerFollow-up AnswerFollow-up
Participant race/ethnicity characteristics Male 45.4 Male 45.4
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Participant age, continuous 62.6 62.6
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21 21
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98 98
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Age >=50, % 30.6% 30.6%
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Participants with Un/Complicated Diverticulitis Complicated diverticulitis 18.5 Complicated diverticulitis 18.5
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Uncomplicated diverticulitis 81.5 Uncomplicated diverticulitis 81.5
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Note/Comment about baseline characteristics The data above are for 425 patients, in which only 310 patients underwent colonoscopy
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Alarm symptoms No data entered.



Results & Comparisons


Results Data
Outcome: Colorectal cancer      Population: All Participants
Time Point Measure Colonoscopy


Enter a numeric value or title (required) years

N Analyzed 310
Counts 5
Percentage 1.6
Outcome: Colorectal cancer      Population: <50 years old
Time Point Measure Colonoscopy


Enter a numeric value or title (required) years

N Analyzed 95
Counts 1
Percentage 1.1
Outcome: Colorectal cancer      Population: >50 years old
Time Point Measure Colonoscopy


Enter a numeric value or title (required) years

N Analyzed 215
Counts 4
Percentage 1.9


Quality Dimensions
Dimension Value Notes Comments
Q23: NHLBI - Were eligibility/selection criteria for the study population prespecified and clearly described? Yes
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Q25: NHLBI - Were the outcome measures prespecified, clearly defined, valid, reliable, and assessed consistently across all study participants? Yes
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If this study was an NRCS or a single-group study, did the study report adjusted results that were for differences between groups (in the case of NRCSs) or differences between subgroups (in the case of single group studies)? No
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Quality Rating
No quality rating data was found.