Study Preview
Study Title and Description
Routine Colonoscopy after Acute Uncomplicated Diverticulitis - Challenging a Putative Indication.
Key Questions Addressed
3 | KQ 3: What are the benefits and harms of colonoscopy (or other colon imaging test) following an episode of acute diverticulitis? KQ 3a. What is the incidence of malignant and premalignant colon tumors found by colonoscopy, and what is the incidence of colon cancer mortality among patients undergoing screening? KQ 3b. What are the procedure-related and other harms of colonoscopy or CT colonography? KQ 3c. What is the frequency of inadequate imaging due to intolerance or technical feasibility? • Do the benefits and harms vary by patient characteristics, course of illness, or other factors? |
Primary Publication Information
Title | Routine Colonoscopy after Acute Uncomplicated Diverticulitis - Challenging a Putative Indication. |
Author | Andrade P., Ribeiro A., Ramalho R., Lopes S., Macedo G. |
Country | Department of Gastroenterology, Faculty of Medicine, Centro Hospitalar de São João, Porto, Portugal. |
Year | 2017 |
Numbers |
Pubmed ID: 27941344 |
Secondary Publication Information
There are currently no secondary publications defined for this study.
Extraction Form: KQ 3: Colonoscopy
Arms
Number | Title | Description | Comments |
---|---|---|---|
1 | Colonoscopy |
Question... Follow Up | Answer | Follow-up Answer | |
---|---|---|---|
Study design | Single group, with subgroup analyses | ||
Single group, with subgroup analyses | |||
Single group, with subgroup analyses | |||
Single group, with subgroup analyses | |||
Single group, with subgroup analyses | |||
Single group, with subgroup analyses | |||
Single group, with subgroup analyses | |||
Single group, with subgroup analyses | |||
Single group, with subgroup analyses | |||
if not an RCT, what was the directionality? | Retrospective | ||
Funder | Not reported (or unclear) | ||
Start and end years of the study | 2008 | ||
2013 | |||
Inclusion criteria | patients who underwent a colonoscopy within 1 year after the conservative management of CT-proven acute diverticulitis | ||
Exclusion criteria | emergency surgery, incomplete colonoscopy | ||
Specific population? | No (anyone with Hx diverticulitis) | ||
No (anyone with Hx diverticulitis) | |||
No (anyone with Hx diverticulitis) | |||
No (anyone with Hx diverticulitis) | |||
No (anyone with Hx diverticulitis) | |||
No (anyone with Hx diverticulitis) | |||
No (anyone with Hx diverticulitis) | |||
No (anyone with Hx diverticulitis) | |||
No (anyone with Hx diverticulitis) | |||
Note/Comment about Design (or overall study) | |||
Country | Portugal | ||
Comparison of colonoscopy vs. no colonoscopy? | No | ||
Comparison of diverticulitis vs health control? | No | ||
Subgroup analyses? | Age <> 50 | ||
Other 1 ... | Hinchey Ia vs. Hinchey ≥Ib | ||
Other 2 ... | Abscess on CT vs. No abscess on CT |
Baseline Characteristics
Question | Colonoscopy | Total | Comments | ||
---|---|---|---|---|---|
Answer | Follow-up | Answer | Follow-up | ||
Participant race/ethnicity characteristics | Male | 49.2 | Male | 49.2 | |
Participant age, continuous | 55 | 55 | |||
11.1 | 11.1 | ||||
Age >=50, % | NR | NR | |||
Participants with Un/Complicated Diverticulitis | Not reported | Not reported | |||
Note/Comment about baseline characteristics | No data entered. | ||||
Alarm symptoms | No data entered. |
Results & Comparisons
Results Data
Outcome: Colorectal cancer Population: All Participants | ||
---|---|---|
Time Point | Measure | Colonoscopy |
Enter a numeric value or title (required) years |
N Analyzed | 252 |
Counts | 8 | |
Percentage | 3.2 | |
note | For the variable of "abscess on CT", OR (95% CI): 3.15 (1.586-11.586), p=0.036 in multivariate logistic regression (advanced colonic neoplasia as the outcome) |
Outcome: Colorectal cancer Population: Hinchey Ia | ||
---|---|---|
Time Point | Measure | Colonoscopy |
Enter a numeric value or title (required) years |
N Analyzed | 209 |
Counts | 1 | |
Percentage | 0.5 | |
note | For the variable of Hinchey classification, OR (95% CI): 3.37 (1.547-13.547), p=0.035 in multivariate logistic regression |
Outcome: Colorectal cancer Population: Hinchey ≥Ib | ||
---|---|---|
Time Point | Measure | Colonoscopy |
Enter a numeric value or title (required) years |
N Analyzed | 43 |
Counts | 7 | |
Percentage | 16.3 |
Outcome: Adenomas, multiple Population: All Participants | ||
---|---|---|
Time Point | Measure | Colonoscopy |
Enter a numeric value or title (required) years |
N Analyzed | 252 |
Counts | 13 | |
Percentage | 5.1 |
Outcome: Adenomas, multiple Population: Hinchey Ia | ||
---|---|---|
Time Point | Measure | Colonoscopy |
Enter a numeric value or title (required) years |
N Analyzed | 209 |
Counts | 11 | |
Percentage | 5.3 |
Outcome: Adenomas, multiple Population: Hinchey ≥Ib | ||
---|---|---|
Time Point | Measure | Colonoscopy |
Enter a numeric value or title (required) years |
N Analyzed | 43 |
Counts | 2 | |
Percentage | 4.7 |
Outcome: Failed/incomplete procedure Population: All Participants | ||
---|---|---|
Time Point | Measure | Colonoscopy |
Enter a numeric value or title (required) years |
N Analyzed | 261 |
Counts | 9 | |
Percentage | 3.4 |
Outcome: Advance Adenoma Population: All Participants | ||
---|---|---|
Time Point | Measure | Colonoscopy |
Enter a numeric value or title (required) years |
N Analyzed | 252 |
Counts | 13 | |
Percentage | 5.1 | |
note |
Quality Dimensions
Dimension | Value | Notes | Comments |
---|---|---|---|
Q23: NHLBI - Were eligibility/selection criteria for the study population prespecified and clearly described? | Yes | ||
Q25: NHLBI - Were the outcome measures prespecified, clearly defined, valid, reliable, and assessed consistently across all study participants? | Yes | ||
If this study was an NRCS or a single-group study, did the study report adjusted results that were for differences between groups (in the case of NRCSs) or differences between subgroups (in the case of single group studies)? | Yes |
Quality Rating
No quality rating data was found.