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Study Title and Description

Colonoscopy and flexible sigmoidoscopy for follow-up of patients with left-sided diverticulitis.



Key Questions Addressed
3 KQ 3: What are the benefits and harms of colonoscopy (or other colon imaging test) following an episode of acute diverticulitis? KQ 3a. What is the incidence of malignant and premalignant colon tumors found by colonoscopy, and what is the incidence of colon cancer mortality among patients undergoing screening? KQ 3b. What are the procedure-related and other harms of colonoscopy or CT colonography? KQ 3c. What is the frequency of inadequate imaging due to intolerance or technical feasibility? • Do the benefits and harms vary by patient characteristics, course of illness, or other factors?
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Primary Publication Information
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TitleData
Title Colonoscopy and flexible sigmoidoscopy for follow-up of patients with left-sided diverticulitis.
Author Abdulazeez Z., Kukreja N., Qureshi N., Lascelles S.
Country Medway Maritime Hospital, Gillingham, UK.
Year 2020
Numbers Pubmed ID: 32820657

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: KQ 3: Colonoscopy
Arms
Number Title Description Comments
1 Colonoscopy
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2 Flexible sigmoidoscopy
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Design Details
Question... Follow Up Answer Follow-up Answer
Study design Single group, with subgroup analyses
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if not an RCT, what was the directionality? Retrospective
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Funder Non-industry (fully)
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Start and end years of the study 2016
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2019
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Inclusion criteria Post acute left-sided diverticulitis endoscopy
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Exclusion criteria Right sided diverticulitis, did not follow up for endoscopy
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Specific population? No (anyone with Hx diverticulitis)
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Age criteria (define) ... >=18
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Note/Comment about Design (or overall study)
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Comparison of colonoscopy vs. no colonoscopy? No
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Comparison of diverticulitis vs health control? No
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Subgroup analyses? ... Other 1 ... Colonoscopy vs. flex sig
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Baseline Characteristics
Question Colonoscopy Flexible sigmoidoscopy Total Comments
AnswerFollow-up AnswerFollow-up AnswerFollow-up
Participant race/ethnicity characteristics Male 35 Male 37
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Participant age, continuous 70 72
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10.2 SD 13.9 SD
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46 28
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90 91
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Age >=50, % NR
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Participants with Un/Complicated Diverticulitis Not reported
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Note/Comment about baseline characteristics No data entered.
Alarm symptoms NR
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Results & Comparisons


Results Data
Outcome: Colorectal cancer      Population: All Participants
Time Point Measure Colonoscopy Flexible sigmoidoscopy


NA years

 N Analyzed 120 120
Counts 0 0
Outcome: Procedural complication      Population: All Participants
Time Point Measure Colonoscopy Flexible sigmoidoscopy


NA years

 N Analyzed 120 120
Counts 0 0
Outcome: Failed/incomplete procedure      Population: All Participants
Time Point Measure Colonoscopy Flexible sigmoidoscopy


NA years

 N Analyzed 120 120
Counts 5 3


Quality Dimensions
Dimension Value Notes Comments
Q23: NHLBI - Were eligibility/selection criteria for the study population prespecified and clearly described? No Inadequate info about possible complicated diverticulitis
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Q25: NHLBI - Were the outcome measures prespecified, clearly defined, valid, reliable, and assessed consistently across all study participants? No Vague and incomplete (noncancers not adequately reported)
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If this study was an NRCS or a single-group study, did the study report adjusted results that were for differences between groups (in the case of NRCSs) or differences between subgroups (in the case of single group studies)? No
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Quality Rating
No quality rating data was found.