Study Title and Description
Safety of non-steroidal anti-inflammatory drugs in the postpartum period among women with hypertensive disorders of pregnancy: a meta-analysis.
Key Questions Addressed
|4||Indirect Evidence (Systematic Reviews): KQ 2 - What are the (comparative) benefits and harms of interventions to treat acute attacks of primary headache in women who are pregnant (or attempting to become pregnant), postpartum, or breastfeeding?|
Primary Publication Information
|Title||Safety of non-steroidal anti-inflammatory drugs in the postpartum period among women with hypertensive disorders of pregnancy: a meta-analysis.|
|Author||Bellos I., Pergialiotis V., Antsaklis A., Loutradis D., Daskalakis G.|
|Country||Laboratory of Experimental Surgery and Surgical Research N.S. Christeas, Athens University Medical School, National and Kapodistrian University of Athens, Greece.|
Pubmed ID: 32068930
Secondary Publication Information
There are currently no secondary publications defined for this study.
Extraction Form: Extraction Form for Indirect Evidence (Systematic Reviews)
No arms have been defined in this extraction form.
|Question... Follow Up||Answer||Follow-up Answer|
|How many DATABASES did the authors search?||4|
|What was the YEAR of the last search?||2019|
|How many STUDIES were included in the review?||10|
|What INTERVENTIONS were addressed?||NSAIDs|
|Were MATERNAL adverse events reported?||Yes|
|Were FETAL/CHILD adverse events reported?||No|
|AMSTAR Item 1 - Did the authors specify the research questions and inclusion criteria for the SR?||Yes|
|AMSTAR Item 4 - Did the SR authors use a comprehensive literature search strategy?||Yes|
|AMSTAR Item 5 - Did the SR authors perform study selection in duplicate?||Unclear|
|AMSTAR Item 6 - Did the SR authors perform data extraction in duplicate, either independently or through verification?||Unclear|
|AMSTAR Item 8 - Did the SR authors describe the included studies in adequate detail?||Yes|
|AMSTAR Item 9 - Did the SR authors use a satisfactory technique for assessing the risk of bias in individual studies that were included in the SR?||Yes|
|AMSTAR Item 12 - Did the SR authors assess the potential impact of risk of bias in individual studies on the summary results, interpretation, discussion?||No|
|AMSTAR Item 11 - If meta-analysis (MA) was performed did the SR authors use appropriate methods for statistical combination of results?||Yes|
|AMSTAR Item 14 - Did the SR authors provide a satisfactory explanation for, and discussion of, any heterogeneity observed in the results of the SR?||Yes|
|AMSTAR Item 16 - Did the SR authors report the lack of significant potential of conflict of interest (COI) regarding conducting the SR?||Yes|
|What was the OVERALL QUALITY OF THE SYSTEMATIC REVIEW||Moderate|
|MATERNAL Adverse Events - ANTEPARTUM|
|MATERNAL Adverse Events - POSTPARTUM||4|
|-2.28 mm Hg|
|-0.38 mm Hg|
|-3.03 mm Hg|
|MATERNAL Adverse Events - DELIVERY|
|MATERNAL Adverse Events - TIMING NOT REPORTED|
|FETAL/CHILD Adverse Events - IN UTERO|
|FETAL/CHILD Adverse Events - PERINATAL|
|FETAL/CHILD Adverse Events - NEONATAL|
|FETAL/CHILD Adverse Events - CHILD|
No baseline characteristics have been defined for this extraction form.
Results & Comparisons
No Results found.
|Arm or Total||Title||Description||Comments|
No quality dimensions were specified.
No quality rating data was found.