Advanced Search

Project: Interventions for Substance Use Disorders in Adolescents: A Systematic Review

Public Report Complete

Project Summary

Title and Description

Key Questions

Associated Extraction Forms

Title Created by Key Questions Addressed Form Notes
Evidence Map Bryant Smith 1

Associated Studies (each link opens a new tab)

Title Author Year
Juvenile drug court: enhancing outcomes by integrating evidence-based treatments. Henggeler SW., Halliday-Boykins CA., Cunningham PB., Randall J., Shapiro SB., Chapman JE. 2006
Sequenced versus coordinated treatment for adolescents with comorbid depressive and substance use disorders. Rohde P., Waldron HB., Turner CW., Brody J., Jorgensen J. 2014
Randomized controlled trial of motivational enhancement therapy with nontreatment-seeking adolescent cannabis users: a further test of the teen marijuana check-up. Walker DD., Stephens R., Roffman R., Demarce J., Lozano B., Towe S., Berg B. 2011
Short- to Midterm Effectiveness of a Brief Motivational Intervention to Reduce Alcohol Use and Related Problems for Alcohol Intoxicated Children and Adolescents in Pediatric Emergency Departments: A Randomized Controlled Trial. Arnaud N., Diestelkamp S., Wartberg L., Sack PM., Daubmann A., Thomasius R. 2017
Screening and brief intervention to reduce marijuana use among youth and young adults in a pediatric emergency department. Bernstein E., Edwards E., Dorfman D., Heeren T., Bliss C., Bernstein J. 2009
A brief motivational interview in a pediatric emergency department, plus 10-day telephone follow-up, increases attempts to quit drinking among youth and young adults who screen positive for problematic drinking. Bernstein J., Heeren T., Edward E., Dorfman D., Bliss C., Winter M., Bernstein E. 2010
Cultural accommodation of group substance abuse treatment for Latino adolescents: Results of an RCT. Burrow-Sánchez JJ., Minami T., Hops H. 2015
Motivational Interviewing to Reduce Substance Use in Adolescents with Psychiatric Comorbidity. Brown RA., Abrantes AM., Minami H., Prince MA., Bloom EL., Apodaca TR., Strong DR., Picotte DM., Monti PM., MacPherson L., Matsko SV., Hunt JI. 2015
Brief Motivational Intervention for Underage Young Adult Drinkers: Results from a Randomized Clinical Trial. Colby SM., Orchowski L., Magill M., Murphy JG., Brazil LA., Apodaca TR., Kahler CW., Barnett NP. 2018
Double-blind placebo-controlled trial of fluoxetine in adolescents with comorbid major depression and an alcohol use disorder. Cornelius JR., Bukstein OG., Wood DS., Kirisci L., Douaihy A., Clark DB. 2009
Alcohol Interventions Among Underage Drinkers in the ED: A Randomized Controlled Trial. Cunningham RM., Chermack ST., Ehrlich PF., Carter PM., Booth BM., Blow FC., Barry KL., Walton MA. 2015
Brief motivational interviewing for teens at risk of substance use consequences: a randomized pilot study in a primary care clinic. D'Amico EJ., Miles JN., Stern SA., Meredith LS. 2008
A randomized clinical trial of family therapy in juvenile drug court. Dakof GA., Henderson CE., Rowe CL., Boustani M., Greenbaum PE., Wang W., Hawes S., Linares C., Liddle HA. 2015
A randomized controlled trial of a brief motivational enhancement for non-treatment-seeking adolescent cannabis users. de Gee EA., Verdurmen JE., Bransen E., de Jonge JM., Schippers GM. 2014
Treatment of co-occurring substance abuse and suicidality among adolescents: a randomized trial. Esposito-Smythers C., Spirito A., Kahler CW., Hunt J., Monti P. 2011
Memantine improves buprenorphine/naloxone treatment for opioid dependent young adults. Gonzalez G., DiGirolamo G., Romero-Gonzalez M., Smelson D., Ziedonis D., Kolodziej M. 2015
A pilot randomized clinical trial testing integrated 12-Step facilitation (iTSF) treatment for adolescent substance use disorder. Kelly JF., Kaminer Y., Kahler CW., Hoeppner B., Yeterian J., Cristello JV., Timko C. 2017
Comparison of pharmacological treatments for opioid-dependent adolescents: a randomized controlled trial. Marsch LA., Bickel WK., Badger GJ., Stothart ME., Quesnel KJ., Stanger C., Brooklyn J. 2005
Seeking safety therapy for adolescent girls with PTSD and substance use disorder: a randomized controlled trial. Najavits LM., Gallop RJ., Weiss RD. 2006
Comparison of disulfiram and placebo in treatment of alcohol dependence of adolescents. Niederhofer H., Staffen W. 2003
Reduction of alcohol drinking in young adults by naltrexone: a double-blind, placebo-controlled, randomized clinical trial of efficacy and safety. O'Malley SS., Corbin WR., Leeman RF., DeMartini KS., Fucito LM., Ikomi J., Romano DM., Wu R., Toll BA., Sher KJ., Gueorguieva R., Kranzler HR. 2015
Cognitive behavioral therapy-based brief intervention for volatile substance misusers during adolescence: a follow-up study. Ögel K., Coskun S. 2011
The short-term safety and efficacy of fluoxetine in depressed adolescents with alcohol and cannabis use disorders: a pilot randomized placebo-controlled trial. Findling RL., Pagano ME., McNamara NK., Stansbrey RJ., Faber JE., Lingler J., Demeter CA., Bedoya D., Reed MD. 2009
Preliminary outcomes from the assertive continuing care experiment for adolescents discharged from residential treatment. Godley MD., Godley SH., Dennis ML., Funk R., Passetti LL. 2002
Adolescent outpatient treatment and continuing care: main findings from a randomized clinical trial. Godley SH., Garner BR., Passetti LL., Funk RR., Dennis ML., Godley MD. 2010
A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents. Gray KM., Carpenter MJ., Baker NL., DeSantis SM., Kryway E., Hartwell KJ., McRae-Clark AL., Brady KT. 2012
An independent replication of the Adolescent-Community Reinforcement Approach with justice-involved youth. Henderson CE., Wevodau AL., Henderson SE., Colbourn SL., Gharagozloo L., North LW., Lotts VA. 2016
Randomized Trial of Family Therapy Versus Nonfamily Treatment for Adolescent Behavior Problems in Usual Care. Hogue A., Dauber S., Henderson CE., Bobek M., Johnson C., Lichvar E., Morgenstern J. 2015
Efficacy of outpatient aftercare for adolescents with alcohol use disorders: a randomized controlled study. Kaminer Y., Burleson JA., Burke RH. 2008
Brief motivational intervention with homeless adolescents: evaluating effects on substance use and service utilization. Baer JS., Garrett SB., Beadnell B., Wells EA., Peterson PL. 2007
Comparing culturally accommodated versus standard group CBT for Latino adolescents with substance use disorders: a pilot study. Burrow-Sanchez JJ., Wrona M. 2012
Integrated family and cognitive-behavioral therapy for adolescent substance abusers: a stage I efficacy study. Latimer WW., Winters KC., D'Zurilla T., Nichols M. 2003
First Evaluation of a Contingency Management Intervention Addressing Adolescent Substance Use and Sexual Risk Behaviors: Risk Reduction Therapy for Adolescents. Letourneau EJ., McCart MR., Sheidow AJ., Mauro PM. 2017
Treating adolescent drug abuse: a randomized trial comparing multidimensional family therapy and cognitive behavior therapy. Liddle HA., Dakof GA., Turner RM., Henderson CE., Greenbaum PE. 2008
Multidimensional Family Therapy as a community-based alternative to residential treatment for adolescents with substance use and co-occurring mental health disorders. Liddle HA., Dakof GA., Rowe CL., Henderson C., Greenbaum P., Wang W., Alberga L. 2018
Double-blind fluoxetine trial in comorbid MDD-CUD youth and young adults. Cornelius JR., Bukstein OG., Douaihy AB., Clark DB., Chung TA., Daley DC., Wood DS., Brown SJ. 2010
A randomized controlled trial of buprenorphine taper duration among opioid-dependent adolescents and young adults. Marsch LA., Moore SK., Borodovsky JT., Solhkhah R., Badger GJ., Semino S., Jarrett K., Condon KD., Rossettie K., Vincent P., Hajizadeh N., Ducat E. 2016
An evaluation of a brief motivational intervention among young ecstasy and cocaine users: no effect on substance and alcohol use outcomes. Marsden J., Stillwell G., Barlow H., Boys A., Taylor C., Hunt N., Farrell M. 2006
The adolescent cannabis check-up: randomized trial of a brief intervention for young cannabis users. Martin G., Copeland J. 2008
Peer Network Counseling with Urban Adolescents: A Randomized Controlled Trial with Moderate Substance Users. Mason M., Light J., Campbell L., Keyser-Marcus L., Crewe S., Way T., Saunders H., King L., Zaharakis NM., McHenry C. 2015
The efficacy of single-session motivational interviewing in reducing drug consumption and perceptions of drug-related risk and harm among young people: results from a multi-site cluster randomized trial. McCambridge J., Strang J. 2004
Randomized controlled trial of motivational interviewing compared with drug information and advice for early intervention among young cannabis users. McCambridge J., Slym RL., Strang J. 2008
Effects of naltrexone on adolescent alcohol cue reactivity and sensitivity: an initial randomized trial. Miranda R., Ray L., Blanchard A., Reynolds EK., Monti PM., Chun T., Justus A., Swift RM., Tidey J., Gwaltney CJ., Ramirez J. 2014
Topiramate and motivational enhancement therapy for cannabis use among youth: a randomized placebo-controlled pilot study. Miranda R., Treloar H., Blanchard A., Justus A., Monti PM., Chun T., Swift R., Tidey JW., Gwaltney CJ. 2017
A randomized controlled trial of an online relapse prevention program for adolescents in substance abuse treatment Kimberlee J. Trudeau, Ryan A. Black, Jody L. Kamon, Steve Sussman 2017
Multidimensional family therapy for adolescent drug abuse: results of a randomized clinical trial. Liddle HA., Dakof GA., Parker K., Diamond GS., Barrett K., Tejeda M. 2001
Brief intervention for harm reduction with alcohol-positive older adolescents in a hospital emergency department. Monti PM., Colby SM., Barnett NP., Spirito A., Rohsenow DJ., Myers M., Woolard R., Lewander W. 1999
Multidimensional family therapy lowers the rate of cannabis dependence in adolescents: a randomised controlled trial in Western European outpatient settings. Rigter H., Henderson CE., Pelc I., Tossmann P., Phan O., Hendriks V., Schaub M., Rowe CL. 2013
Preliminary results for an adaptive family treatment for drug abuse in Hispanic youth. Santisteban DA., Mena MP., McCabe BE. 2011
Brief intervention for drug-abusing adolescents in a school setting: outcomes and mediating factors. Winters KC., Fahnhorst T., Botzet A., Lee S., Lalone B. 2012
Ecologically based family therapy outcome with substance abusing runaway adolescents. Slesnick N., Prestopnik JL. 2005
Treatment outcome for street-living, homeless youth. Slesnick N., Prestopnik JL., Meyers RJ., Glassman M. 2007
Brief strategic family therapy versus treatment as usual: results of a multisite randomized trial for substance using adolescents. Robbins MS., Feaster DJ., Horigian VE., Rohrbaugh M., Shoham V., Bachrach K., Miller M., Burlew KA., Hodgkins C., Carrion I., Vandermark N., Schindler E., Werstlein R., Szapocznik J. 2011
A randomized clinical trial of a brief motivational intervention for alcohol-positive adolescents treated in an emergency department. Spirito A., Monti PM., Barnett NP., Colby SM., Sindelar H., Rohsenow DJ., Lewander W., Myers M. 2004
Enhancing the effectiveness of juvenile drug courts by integrating evidence-based practices. Henggeler SW., McCart MR., Cunningham PB., Chapman JE. 2012
Motivational Interviewing With and Without Normative Feedback for Adolescents With Substance Use Problems: A Preliminary Study. Smith DC., Ureche DJ., Davis JP., Walters ST. 2015
The efficacy of two adolescent substance abuse treatments and the impact of comorbid depression: results of a small randomized controlled trial. Santisteban DA., Mena MP., Muir J., McCabe BE., Abalo C., Cummings AM. 2015
Brief intervention for students with methamphetamine use disorders: a randomized controlled trial. Srisurapanont M., Sombatmai S., Boripuntakul T. -- Not Found --
Abstinence based incentives plus parent training for adolescent alcohol and other substance misuse. Stanger C., Scherer EA., Babbin SF., Ryan SR., Budney AJ. 2017
Comparative efficacy of family and group treatment for adolescent substance abuse. Smith DC., Hall JA., Williams JK., An H., Gotman N. 2006
Motivational enhancement therapy for adolescent marijuana users: a preliminary randomized controlled trial. Walker DD., Roffman RA., Stephens RS., Wakana K., Berghuis J., Kim W. 2006
Intervention with substance-abusing runaway adolescents and their families: results of a randomized clinical trial. Slesnick N., Erdem G., Bartle-Haring S., Brigham GS. 2013
Effectiveness of a brief-intervention and continuity of care in enhancing attendance for treatment by adolescent substance users. Tait RJ., Hulse GK., Robertson SI. 2004
Comparison of family therapy outcome with alcohol-abusing, runaway adolescents. Slesnick N., Prestopnik JL. 2009
Clinic- and home-based contingency management plus parent training for adolescent cannabis use disorders. Stanger C., Ryan SR., Scherer EA., Norton GE., Budney AJ. 2015
A randomized controlled trial of guided self-change with minority adolescents. Wagner EF., Hospital MM., Graziano JN., Morris SL., Gil AG. 2014
A randomized trial of contingency management for adolescent marijuana abuse and dependence. Stanger C., Budney AJ., Kamon JL., Thostensen J. 2009
A randomized clinical trial of a targeted intervention to moderate alcohol use and alcohol-related problems in at-risk adolescents. Thush C., Wiers RW., Theunissen N., Van den Bosch J., Opdenacker J., van Empelen P., Moerbeek M., Feron FJ. 2007
A randomized controlled trial of fluoxetine and cognitive behavioral therapy in adolescents with major depression, behavior problems, and substance use disorders. Riggs PD., Mikulich-Gilbertson SK., Davies RD., Lohman M., Klein C., Stover SK. 2007
Augmenting brief interventions for adolescent marijuana users: The impact of motivational check-ins. Walker DD., Stephens RS., Blevins CE., Banes KE., Matthews L., Roffman RA. 2016
Motivational interviewing to reduce substance-related consequences: effects for incarcerated adolescents with depressed mood. Stein LA., Clair M., Lebeau R., Colby SM., Barnett NP., Golembeske C., Monti PM. 2011
Short-term effects of a brief motivational intervention to reduce alcohol and drug risk among homeless adolescents. Peterson PL., Baer JS., Wells EA., Ginzler JA., Garrett SB. 2006
Psychotherapies for adolescent substance abusers: a pilot study. Kaminer Y., Burleson JA., Blitz C., Sussman J., Rounsaville BJ. 1998
The efficacy of structural ecosystems therapy with drug-abusing/dependent African American and Hispanic American adolescents. Robbins MS., Szapocznik J., Dillon FR., Turner CW., Mitrani VB., Feaster DJ. 2008
Treatment outcomes for adolescent substance abuse at 4- and 7-month assessments. Waldron HB., Slesnick N., Brody JL., Turner CW., Peterson TR. 2001
Double-blind and placebo-controlled study of lithium for adolescent bipolar disorders with secondary substance dependency. Geller B., Cooper TB., Sun K., Zimerman B., Frazier J., Williams M., Heath J. 1998
Cognitive-behavioral coping skills and psychoeducation therapies for adolescent substance abuse. Kaminer Y., Burleson JA., Goldberger R. 2002
RCT of a promising vocational/employment program for high-risk juvenile offenders. Schaeffer CM., Henggeler SW., Ford JD., Mann M., Chang R., Chapman JE. 2014
Community partnership to affect substance abuse among Native American adolescents. Lowe J., Liang H., Riggs C., Henson J., Elder T. 2012
Family-Based HIV and Sexually Transmitted Infection Risk Reduction for Drug-Involved Young Offenders: 42-Month Outcomes. Rowe CL., Alberga L., Dakof GA., Henderson CE., Ungaro R., Liddle HA. 2016
Eliminating (almost) treatment dropout of substance abusing or dependent delinquents through home-based multisystemic therapy. Henggeler SW., Pickrel SG., Brondino MJ., Crouch JL. 1996
Assessment of change in scores on personal control orientation and use of drugs and alcohol of adolescents who participate in a cognitively oriented pretreatment intervention. Figurelli GA., Hartman BW., Kowalski FX. 1994
Brief intervention for drug-abusing adolescents in a school setting. Winters KC., Leitten W. 2007
Comparison of cyanamide and placebo in the treatment of alcohol dependence of adolescents. Niederhofer H., Staffen W., Mair A. -- Not Found --
Effectiveness of a web-based brief alcohol intervention and added value of normative feedback in reducing underage drinking: a randomized controlled trial. Spijkerman R., Roek MA., Vermulst A., Lemmers L., Huiberts A., Engels RC. 2010
A comparison of three interventions for homeless youth evidencing substance use disorders: results of a randomized clinical trial. Slesnick N., Guo X., Brakenhoff B., Bantchevska D. 2015
A controlled evaluation and description of individual-cognitive problem solving and family-behavior therapies in dually-diagnosed conduct-disordered and substance-dependent youth Azrin 2001
Consejo breve para adolescentes escolares que abusan del alcohol. = School-based brief counseling for teenage drinkers Martínez Martínez, KI; Pedroza Cabrera, FJ; Vacío Muro, MdlA; Jiménez Pérez, AL; Salazar Garza, SL 2008
Randomized, controlled trial of atomoxetine for attention-deficit/hyperactivity disorder in adolescents with substance use disorder. Thurstone C., Riggs PD., Salomonsen-Sautel S., Mikulich-Gilbertson SK. 2010
Individual and family motivational interventions for alcohol-positive adolescents treated in an emergency department: results of a randomized clinical trial. Spirito A., Sindelar-Manning H., Colby SM., Barnett NP., Lewander W., Rohsenow DJ., Monti PM. 2011
A randomized controlled trial of pemoline for attention-deficit/hyperactivity disorder in substance-abusing adolescents. Riggs PD., Hall SK., Mikulich-Gilbertson SK., Lohman M., Kayser A. 2004
Parent and Adolescent Motivational Enhancement Intervention for Substance-Using, Truant Adolescents: A Pilot Randomized Trial. Spirito A., Hernandez L., Cancilliere MK., Graves HR., Rodriguez AM., Operario D., Jones R., Barnett NP. 2017
An open randomized trial comparing disulfiram and naltrexone in adolescents with alcohol dependence De Sousa, A; De Sousa, A 2008
Extended vs short-term buprenorphine-naloxone for treatment of opioid-addicted youth: a randomized trial. Woody GE., Poole SA., Subramaniam G., Dugosh K., Bogenschutz M., Abbott P., Patkar A., Publicker M., McCain K., Potter JS., Forman R., Vetter V., McNicholas L., Blaine J., Lynch KG., Fudala P. 2008
Early intervention for adolescent substance abuse: pretreatment to posttreatment outcomes of a randomized clinical trial comparing multidimensional family therapy and peer group treatment. Liddle HA., Rowe CL., Dakof GA., Ungaro RA., Henderson CE. 2004
Randomized controlled trial of osmotic-release methylphenidate with cognitive-behavioral therapy in adolescents with attention-deficit/hyperactivity disorder and substance use disorders. Riggs PD., Winhusen T., Davies RD., Leimberger JD., Mikulich-Gilbertson S., Klein C., Macdonald M., Lohman M., Bailey GL., Haynes L., Jaffee WB., Haminton N., Hodgkins C., Whitmore E., Trello-Rishel K., Tamm L., Acosta MC., Royer-Malvestuto C., Subramaniam G., Fishman M., Holmes BW., Kaye ME., Vargo MA., Woody GE., Nunes EV., Liu D. 2011
Contingency management in community programs treating adolescent substance abuse: a feasibility study. Killeen TK., McRae-Clark AL., Waldrop AE., Upadhyaya H., Brady KT. 2012
Comparison of naltrexone and placebo in treatment of alcohol dependence of adolescents Niederhofer 2003
Youth drug abuse treatment: a controlled outcome study Azrin 1994
A comparative study using Disulfiram and Naltrexone in alcohol-dependent adolescents De Sousa, A 2014
Treating adolescent drug abuse: a comparison of family systems therapy, group therapy, and family drug education Joanning 1992
Efficacy and Tolerability of Topiramate in Treatment of Bipolar Mania and Alcohol Use in Adolescents and Young Adults Delbello M 2017
Efficacy Study of Quetiapine Plus Topiramate for Reducing Cannabis Consumption and Bipolar Mania Delbello M 2017
A Controlled Study of Inpatient vs. Outpatient Treatment of Delinquent Drug Abusing Adolescents: One Year Results Amini, F and Zilberg, Nj and Burke, El and Salasnek, S 1982
Family therapy vs parent groups: effects on adolescent drug abusers Friedeman 1989
Moderators of outcome in a web-based substance use intervention for adolescents Arnaud 2015
Screening and brief intervention with adolescents with risky alcohol use in school-based health centers: A randomized clinical trial of the Check Yourself tool. McCarty CA., Gersh E., Katzman K., Lee CM., Sucato GS., Richardson LP. 2019
Brief motivational interviewing intervention to reduce alcohol and marijuana use for at-risk adolescents in primary care. D'Amico EJ., Parast L., Shadel WG., Meredith LS., Seelam R., Stein BD. 2018
Substance use and social stability of homeless youth: A comparison of three interventions. Zhang J., Slesnick N. 2018
A pilot randomized controlled trial of a technology-based substance use intervention for youth exiting foster care Braciszewski, Jordan M.;Tzilos Wernette, Golfo K.; Moore, Roland S.; Bock, Beth C.; Stout, Robert L; Chamberlain, Patricia 2018
A randomized controlled trial of a group motivational interviewing intervention for adolescents with a first time alcohol or drug offense. D'Amico EJ., Hunter SB., Miles JN., Ewing BA., Osilla KC. -- Not Found --
A randomized trial of Volunteer Recovery Support for Adolescents (VRSA) following residential treatment discharge. Godley MD., Passetti LL., Hunter BD., Greene AR., White WL. 2019
Brief alcohol intervention for risky drinking in young people aged 14–15 years in secondary schools: the SIPS JR-HIGH RCT Emma L Giles, Grant J McGeechan, Simon Coulton, Paolo Deluca, Colin Drummond, Denise Howel, Eileen Kaner, Elaine McColl, Ruth McGovern, Stephanie Scott, Elaine Stamp, Harry Sumnall, Liz Todd, Luke Vale, Viviana Albani, Sadie Boniface, Jennifer Ferguson, Eilish Gilvarry, Nadine Hendrie, Nicola Howe, Helen Mossop, Amy Ramsay, Grant Stanley and Dorothy Newbury-Birch 2019
Impact of Brief Intervention Services on Drug Using Truant Youth Arrest Charges over Time. Dembo R., Briones-Robinson R., Wareham J., Schmeidler J., Winters KC., Barrett K., Ungaro R., Karas LM., Belenko S. 2014
Outcomes of a family-based HIV prevention intervention for substance using juvenile offenders. Tolou-Shams M., Dauria E., Conrad SM., Kemp K., Johnson S., Brown LK. 2017
The Cannabis Youth Treatment (CYT) Study: main findings from two randomized trials. Dennis M., Godley SH., Diamond G., Tims FM., Babor T., Donaldson J., Liddle H., Titus JC., Kaminer Y., Webb C., Hamilton N., Funk R. 2004
The Cannabis Youth Treatment (CYT) Study: main findings from two randomized trials. Dennis M., Godley SH., Diamond G., Tims FM., Babor T., Donaldson J., Liddle H., Titus JC., Kaminer Y., Webb C., Hamilton N., Funk R. 2004
The effectiveness of a web-based brief alcohol intervention in reducing heavy drinking among adolescents aged 15-20 years with a low educational background: a two-arm parallel group cluster randomized controlled trial. Voogt CV., Kleinjan M., Poelen EA., Lemmers LA., Engels RC. 2013

Creative Commons LicenseThis graphic notice indicates that you are leaving this Federal Government Web site and entering a non-Federal Web site. Creative Commons  
The data contained in this project are distributed under the terms of the Creative Commons Attribution-NonCommerical license, which permits the use, dissemination, and reproduction in any medium, provided the original work is properly cited, and that the use is non-commercial and otherwise in compliance with the license. See: