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Study Title and Description

Multidimensional family therapy for adolescent drug abuse: results of a randomized clinical trial.



Key Questions Addressed
1 Evidence map
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Primary Publication Information
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TitleData
Title Multidimensional family therapy for adolescent drug abuse: results of a randomized clinical trial.
Author Liddle HA., Dakof GA., Parker K., Diamond GS., Barrett K., Tejeda M.
Country Center for Treatment Research on Adolescent Drug Abuse, Department of Epidemiology and Public Health, University of Miami School of Medicine, Florida 33136, USA. hliddle@med.miami.edu
Year 2001
Numbers Pubmed ID: 11727882

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Evidence Map
Arms
Number Title Description Comments
1 Fam_b MDFT
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2 PeerGroup adolescent group therapy (AGT),
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3 Fam_a multifamily educational intervention (MEI).
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Design Details
Question... Follow Up Answer Follow-up Answer
Should this citation be included? Yes
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Does this paper originate from a primary study of interest? No
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Ages eligible (in years) 13
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18
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Total sample size (in all arms) 182
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Age distribution of enrolled population (in years) 15.9
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Substance used Alcohol
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Cannabis
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Interventions studied? Behavioral
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Outcome? Objective measurement of use/abstinence and/or intensity
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Self report of use/abstinence and/or intensity
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School or Educational
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Family functioning
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Peer functioning
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Age variation of enrolled population (in years) 1.4
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Study type RCT
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Is any arm a brief intervention (or single session)? No
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Income level of country(ies) of origin ... Country(ies) name(s) Unclear ... United States
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Results & Comparisons


Results Data
Outcome: nos use days      Population: All Participants
Time Point Measure Fam_b PeerGroup Fam_a


0 months

N Analyzed 47 52 53
Mean 9.89 8.83 10.03
SD 3.79 2.76 3.45


5.5 months

N Analyzed 47 52 53
Mean 4.79 7.33 7.26
SD 3.2 3.41 5.05


6 months

N Analyzed 47 52 53
Mean 5.04 6.21 6.87
SD 3.77 3.66 3.79


12 months

N Analyzed 47 52 53
Mean 4.25 5.08 7.26
SD 2.98 3.71 3.97


Quality Dimensions
Dimension Value Notes Comments
Intention-to-treat-analysis: Bias due to incomplete reporting and analysis according to group allocation No Data
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Group similarity at baseline (selection bias): Selection bias due to dissimilarity at baseline for the most important prognostic indicators No Family competence differed, but not accounted for
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Co-interventions (performance bias): Performance bias because co-interventions were different across groups Yes
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Compliance (performance bias): Performance bias due to inappropriate compliance with interventions across groups No 38% attrition
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Timing of outcome assessments (detection bias): Detection bias because important outcomes were not measured at the same time across groups Yes
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Additional Bias: Bias due to problems not covered elsewhere in the table. If yes, describe them in the Notes. No
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Random sequence generation (selection bias): Selection bias (biased allocation to interventions) due to inadequate generation of a randomized sequence Unclear
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Allocation concealment (selection bias): Selection bias (biased allocation to interventions) due to inadequate concealment of allocations prior to assignment Unclear
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Blinding of participants (performance bias): Performance bias due to knowledge of the allocated interventions by participants during the study High
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Blinding of personnel/ care providers (performance bias): Performance bias due to knowledge of the allocated interventions by personnel/care providers during the study. High
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Blinding of outcome assessor (detection bias): Detection bias due to knowledge of the allocated interventions by outcome assessors. Low
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Incomplete outcome data (attrition bias): Attrition bias due to amount, nature or handling of incomplete outcome data Unclear nd on number analyzed
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Selective Reporting (reporting bias): Reporting bias due to selective outcome reporting
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Quality Rating
No quality rating data was found.