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Study Title and Description

A controlled evaluation and description of individual-cognitive problem solving and family-behavior therapies in dually-diagnosed conduct-disordered and substance-dependent youth



Key Questions Addressed
1 Evidence map
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Primary Publication Information
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TitleData
Title A controlled evaluation and description of individual-cognitive problem solving and family-behavior therapies in dually-diagnosed conduct-disordered and substance-dependent youth
Author Azrin
Country
Year 2001
Numbers Pubmed ID: 2002-13926-001

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Evidence Map
Arms
Number Title Description Comments
1 CBT
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2 Fam
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Design Details
Question... Follow Up Answer Follow-up Answer
Should this citation be included? Yes
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Does this paper originate from a primary study of interest? No
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Ages eligible (in years) 12
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17
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Total sample size (in all arms) 56
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Age distribution of enrolled population (in years) 15.4
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Substance used SUD (not further described, except maybe excluding nicotine)
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Interventions studied? Behavioral
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Outcome? Objective measurement of use/abstinence and/or intensity
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Self report of use/abstinence and/or intensity
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Other ... conduct, mood
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Age variation of enrolled population (in years) 1.3
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Study type RCT
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Is any arm a brief intervention (or single session)? No
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Income level of country(ies) of origin ... Country(ies) name(s) Unclear ... United States
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Results & Comparisons


Results Data
Outcome: pct abstinent for nos      Population: All Participants
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Percentage 22.22 24.14


6 months

N Analyzed 27 29
Percentage 52 25


12 months

N Analyzed 27 29
Percentage 44.4 45.0
Outcome: nos use days      Population: All Participants
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 14.14 13.62
SD 10.58 10.30
SE


6 months

N Analyzed 27 29
Mean 9.28 9.00
SD 10.23 8.33
SE


12 months

N Analyzed 27 29
Mean 8.35 8.61
SD 9.23 9.76
SE
Outcome: PHYS      Population: 122523
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 23.70 20.06
SD 31.88 25.50
SE


6 months

N Analyzed 27 29
Mean 57.52 67.93
SD 32.78 23.51
SE


12 months

N Analyzed 27 29
Mean 60.61 65.74
SD 27.25 26.90
SE
Outcome: YHPS      Population: 122524
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 15.63 12.17
SD 25.55 23.92
SE


6 months

N Analyzed 27 29
Mean 59.13 63.92
SD 42.52 41.20
SE


12 months

N Analyzed 27 29
Mean 62.10 57.37
SD 36.45 45.69
SE
Outcome: LSS-A      Population: 122525
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 60.85 64.93
SD 37.62 31.34
SE


6 months

N Analyzed 27 29
Mean 77.78 65.57
SD 33.78 36.76
SE


12 months

N Analyzed 27 29
Mean 74.62 75.17
SD 34.97 31.00
SE
Outcome: CBCL      Population: All Participants
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 77.40 74.44
SD 8.45 6.70
SE


6 months

N Analyzed 27 29
Mean 66.67 63.55
SD 12.11 9.10
SE


12 months

N Analyzed 27 29
Mean 64.15 65.83
SD 8.32 10.25
SE
Outcome: YSR      Population: 122527
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 69.03 68.55
SD 10.31 11.00
SE


6 months

N Analyzed 27 29
Mean 65.58 63.27
SD 9.91 6.53
SE


12 months

N Analyzed 27 29
Mean 60.19 60.67
SD 9.00 6.52
SE
Outcome: ECBI      Population: 122528
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 21.52 17.86
SD 6.12 8.52
SE


6 months

N Analyzed 27 29
Mean 11.95 8.58
SD 9.46 9.09
SE


12 months

N Analyzed 27 29
Mean 11.52 8.22
SD 12.02 8.41
SE
Outcome: ECBI      Population: 122529
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 145.93 133.55
SD 35.58 38.26
SE


6 months

N Analyzed 27 29
Mean 110.35 90.72
SD 45.92 36.37
SE


12 months

N Analyzed 27 29
Mean 86.71 94.29
SD 38.10 40.35
SE
Outcome: Arrests      Population: All Participants
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 0.84 0.93
SD 1.02 1.51
SE


6 months

N Analyzed 27 29
Mean 0.42 0.28
SD 0.82 0.48
SE


12 months

N Analyzed 27 29
Mean 0.24 0.51
SD 0.29 0.59
SE
Outcome: YHPS      Population: 122531
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 40.37 28.97
SD 36.64 35.29
SE


6 months

N Analyzed 27 29
Mean 71.48 63.45
SD 39.00 44.18
SE


12 months

N Analyzed 27 29
Mean 59.51 71.27
SD 41.04 35.61
SE
Outcome: PHYS      Population: 122532
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 18.52 32.76
SD 29.18 39.72
SE


6 months

N Analyzed 27 29
Mean 62.22 75.17
SD 40.70 36.02
SE


12 months

N Analyzed 27 29
Mean 75.24 56.95
SD 32.81 43.75
SE
Outcome: CBL      Population: 122533
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 33.78 32.32
SD 7.80 8.01
SE


6 months

N Analyzed 27 29
Mean 37.89 38.05
SD 11.30 11.02
SE


12 months

N Analyzed 27 29
Mean 36.85 40.00
SD 9.15 10.63
SE
Outcome: PHYS      Population: 122534
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 23.70 20.06
SD 31.88 25.50
SE


6 months

N Analyzed 27 29
Mean 57.52 67.93
SD 32.78 23.51
SE


12 months

N Analyzed 27 29
Mean 60.61 65.74
SD 27.25 26.90
SE
Outcome: LSS-A      Population: 122535
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 65.35 63.60
SD 31.89 30.61
SE


6 months

N Analyzed 27 29
Mean 87.41 78.28
SD 17.45 23.77
SE


12 months

N Analyzed 27 29
Mean 83.81 79.24
SD 23.90 25.01
SE
Outcome: BDI      Population: All Participants
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 12.07 12.10
SD 10.20 9.57
SE


6 months

N Analyzed 27 29
Mean 5.80 4.72
SD 7.10 4.80
SE


12 months

N Analyzed 27 29
Mean 4.13 5.07
SD 3.34 6.16
SE
Outcome: LSS-A      Population: 122537
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 63.27 64.50
SD 15.13 11.98
SE


6 months

N Analyzed 27 29
Mean 81.33 74.08
SD 14.48 15.57
SE


12 months

N Analyzed 27 29
Mean 77.72 77.96
SD 14.29 14.13
SE
Outcome: YHPS      Population: 122538
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 54.04 51.47
SD 24.07 21.28
SE


6 months

N Analyzed 27 29
Mean 75.60 72.52
SD 14.34 20.02
SE


12 months

N Analyzed 27 29
Mean 74.27 82.23
SD 18.79 14.18
SE
Outcome: PHYS      Population: 122539
Time Point Measure CBT Fam


0 months

N Analyzed 27 29
Mean 29.02 39.05
SD 57.96 19.97
SE


6 months

N Analyzed 27 29
Mean 57.96 68.48
SD 31.75 22.80
SE


12 months

N Analyzed 27 29
Mean 68.66 61.25
SD 19.14 28.13
SE


Quality Dimensions
Dimension Value Notes Comments
Intention-to-treat-analysis: Bias due to incomplete reporting and analysis according to group allocation No
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Group similarity at baseline (selection bias): Selection bias due to dissimilarity at baseline for the most important prognostic indicators No Dropout (exclusion) related to Externalizing. Not accounted for.
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Co-interventions (performance bias): Performance bias because co-interventions were different across groups No
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Compliance (performance bias): Performance bias due to inappropriate compliance with interventions across groups No But completers analysis only
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Timing of outcome assessments (detection bias): Detection bias because important outcomes were not measured at the same time across groups No
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Additional Bias: Bias due to problems not covered elsewhere in the table. If yes, describe them in the Notes. No
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Random sequence generation (selection bias): Selection bias (biased allocation to interventions) due to inadequate generation of a randomized sequence Low With clumsy matching
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Allocation concealment (selection bias): Selection bias (biased allocation to interventions) due to inadequate concealment of allocations prior to assignment Unclear
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Blinding of participants (performance bias): Performance bias due to knowledge of the allocated interventions by participants during the study High
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Blinding of personnel/ care providers (performance bias): Performance bias due to knowledge of the allocated interventions by personnel/care providers during the study. High
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Blinding of outcome assessor (detection bias): Detection bias due to knowledge of the allocated interventions by outcome assessors. Low
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Incomplete outcome data (attrition bias): Attrition bias due to amount, nature or handling of incomplete outcome data High 36%
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Selective Reporting (reporting bias): Reporting bias due to selective outcome reporting
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Quality Rating
No quality rating data was found.