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Study Title and Description

First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study.



Key Questions Addressed
1 Among pregnant and postpartum women, what is the effectiveness of pharmacologic interventions on maternal outcomes 1a. Among those with a new or preexisting anxiety disorder? 1b. Among those with a new or preexisting depressive disorder? 1c. Among those with a new or preexisting bipolar disorder? 1d. Among those with new or preexisting schizophrenia?
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2 Among pregnant and postpartum women, what is the comparative effectiveness of pharmacologic interventions on maternal outcomes 2a. Among those with a new or preexisting anxiety disorder? 2b. Among those with a new or preexisting depressive disorder? 2c. Among those with a new or preexisting bipolar disorder? 2d. Among those with new or preexisting schizophrenia?
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3 Among reproductive-aged women with any mental health disorder, what are the maternal and fetal harms associated with pharmacologic interventions for a mental health disorder during preconception, pregnancy, and postpartum?
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4 Among reproductive-aged women with any mental health disorder, what are the comparative maternal and fetal harms of pharmacologic interventions for a mental health disorder during preconception, pregnancy, and postpartum?
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Primary Publication Information
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TitleData
Title First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study.
Author Ban L., West J., Gibson JE., Fiaschi L., Sokal R., Doyle P., Hubbard R., Smeeth L., Tata LJ.
Country Division of Epidemiology & Public Health, Nottingham City Hospital, University of Nottingham, Nottingham, United Kingdom.
Year 2014
Numbers Pubmed ID: 24963627

Secondary Publication Information
There are currently no secondary publications defined for this study.


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Results & Comparisons

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