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Study Title and Description

Relapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment.



Key Questions Addressed
1 Among pregnant and postpartum women, what is the effectiveness of pharmacologic interventions on maternal outcomes 1a. Among those with a new or preexisting anxiety disorder? 1b. Among those with a new or preexisting depressive disorder? 1c. Among those with a new or preexisting bipolar disorder? 1d. Among those with new or preexisting schizophrenia?
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2 Among pregnant and postpartum women, what is the comparative effectiveness of pharmacologic interventions on maternal outcomes 2a. Among those with a new or preexisting anxiety disorder? 2b. Among those with a new or preexisting depressive disorder? 2c. Among those with a new or preexisting bipolar disorder? 2d. Among those with new or preexisting schizophrenia?
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3 Among reproductive-aged women with any mental health disorder, what are the maternal and fetal harms associated with pharmacologic interventions for a mental health disorder during preconception, pregnancy, and postpartum?
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4 Among reproductive-aged women with any mental health disorder, what are the comparative maternal and fetal harms of pharmacologic interventions for a mental health disorder during preconception, pregnancy, and postpartum?
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Primary Publication Information
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TitleData
Title Relapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment.
Author Cohen LS., Altshuler LL., Harlow BL., Nonacs R., Newport DJ., Viguera AC., Suri R., Burt VK., Hendrick V., Reminick AM., Loughead A., Vitonis AF., Stowe ZN.
Country Perinatal and Reproductive Psychiatry Clinical Research Program, Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Mass 02114, USA. lcohen2@partners.org
Year 2006
Numbers Pubmed ID: 16449615

Secondary Publication Information
There are currently no secondary publications defined for this study.


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Results & Comparisons

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