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Study Title and Description

Exposure to selective serotonin reuptake inhibitors and the risk of congenital malformations: a nationwide cohort study.



Key Questions Addressed
1 Among pregnant and postpartum women, what is the effectiveness of pharmacologic interventions on maternal outcomes 1a. Among those with a new or preexisting anxiety disorder? 1b. Among those with a new or preexisting depressive disorder? 1c. Among those with a new or preexisting bipolar disorder? 1d. Among those with new or preexisting schizophrenia?
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2 Among pregnant and postpartum women, what is the comparative effectiveness of pharmacologic interventions on maternal outcomes 2a. Among those with a new or preexisting anxiety disorder? 2b. Among those with a new or preexisting depressive disorder? 2c. Among those with a new or preexisting bipolar disorder? 2d. Among those with new or preexisting schizophrenia?
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3 Among reproductive-aged women with any mental health disorder, what are the maternal and fetal harms associated with pharmacologic interventions for a mental health disorder during preconception, pregnancy, and postpartum?
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4 Among reproductive-aged women with any mental health disorder, what are the comparative maternal and fetal harms of pharmacologic interventions for a mental health disorder during preconception, pregnancy, and postpartum?
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Primary Publication Information
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TitleData
Title Exposure to selective serotonin reuptake inhibitors and the risk of congenital malformations: a nationwide cohort study.
Author Jimenez-Solem E., Andersen JT., Petersen M., Broedbaek K., Jensen JK., Afzal S., Gislason GH., Torp-Pedersen C., Poulsen HE.
Country Laboratory of Clinical Pharmacology, Rigshospitalet, Copenhagen, Denmark.
Year 2012
Numbers Pubmed ID: 22710132

Secondary Publication Information
There are currently no secondary publications defined for this study.


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Results & Comparisons

No Results found.