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Study Title and Description

Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study.



Key Questions Addressed
7 Key Question 7. What is the effectiveness of currently recommended antiviral treatments in achieving a SVR in patients with HCV infection?
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8 Key Question 8. What are the harms of currently recommended antiviral treatments?
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Primary Publication Information
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TitleData
Title Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study.
Author Lawitz E., Sulkowski MS., Ghalib R., Rodriguez-Torres M., Younossi ZM., Corregidor A., DeJesus E., Pearlman B., Rabinovitz M., Gitlin N., Lim JK., Pockros PJ., Scott JD., Fevery B., Lambrecht T., Ouwerkerk-Mahadevan S., Callewaert K., Symonds WT., Picchio G., Lindsay KL., Beumont M., Jacobson IM.
Country Texas Liver Institute, University of Texas Health Science Center, San Antonio, TX, USA. Electronic address: lawitz@txliver.com.
Year 2014
Numbers Pubmed ID: 25078309

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Questions 1-9


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