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Project: Obstructive Sleep Apnea: CPAP and AHI vs. outcomes

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Title and Description


Key Questions


Associated Extraction Forms

Title Created by Key Questions Addressed Form Notes
KQ 2 Monika Reddy Bhuma 1
AHI Ethan Balk 2


Associated Studies (each link opens a new tab)

Title Author Year
Effect of Positive Airway Pressure on Cardiovascular Outcomes in Coronary Artery Disease Patients with Nonsleepy Obstructive Sleep Apnea. The RICCADSA Randomized Controlled Trial. zzz_Peker Y., Glantz H., Eulenburg C., Wegscheider K., Herlitz J., Thunström E. 2016
Effect of Positive Airway Pressure on Cardiovascular Outcomes in Coronary Artery Disease Patients with Nonsleepy Obstructive Sleep Apnea. The RICCADSA Randomized Controlled Trial. zzz_Peker Y., Glantz H., Eulenburg C., Wegscheider K., Herlitz J., Thunström E. 2016
Nonfatal and fatal cardiovascular disease events in CPAP compliant obstructive sleep apnea patients. Myllylä M., Hammais A., Stepanov M., Anttalainen U., Saaresranta T., Laitinen T. 2019
Nonfatal and fatal cardiovascular disease events in CPAP compliant obstructive sleep apnea patients. zzz_Myllylä M., Hammais A., Stepanov M., Anttalainen U., Saaresranta T., Laitinen T. 2019
Nonfatal and fatal cardiovascular disease events in CPAP compliant obstructive sleep apnea patients. zzz_Myllylä M., Hammais A., Stepanov M., Anttalainen U., Saaresranta T., Laitinen T. 2019
Effect of Positive Airway Pressure on Cardiovascular Outcomes in Coronary Artery Disease Patients with Nonsleepy Obstructive Sleep Apnea. The RICCADSA Randomized Controlled Trial. zzz_Peker Y., Glantz H., Eulenburg C., Wegscheider K., Herlitz J., Thunström E. 2016
Nonfatal and fatal cardiovascular disease events in CPAP compliant obstructive sleep apnea patients. zzz_Myllylä M., Hammais A., Stepanov M., Anttalainen U., Saaresranta T., Laitinen T. 2019
Nonfatal and fatal cardiovascular disease events in CPAP compliant obstructive sleep apnea patients. zzz_Myllylä M., Hammais A., Stepanov M., Anttalainen U., Saaresranta T., Laitinen T. 2019
Effect of Positive Airway Pressure on Cardiovascular Outcomes in Coronary Artery Disease Patients with Nonsleepy Obstructive Sleep Apnea. The RICCADSA Randomized Controlled Trial. Peker Y., Glantz H., Eulenburg C., Wegscheider K., Herlitz J., Thunström E. 2016
Role of sleep apnea and continuous positive airway pressure therapy in the incidence of stroke or coronary heart disease in women. zzz_Campos-Rodriguez F., Martinez-Garcia MA., Reyes-Nuñez N., Caballero-Martinez I., Catalan-Serra P., Almeida-Gonzalez CV. 2014
Association of Positive Airway Pressure Prescription With Mortality in Patients With Obesity and Severe Obstructive Sleep Apnea: The Sleep Heart Health Study. Lisan Q., Van Sloten T., Marques Vidal P., Haba Rubio J., Heinzer R., Empana JP. 2019
Cardiovascular mortality in obstructive sleep apnoea treated with continuous positive airway pressure or oral appliance: an observational study. zzz_Anandam A., Patil M., Akinnusi M., Jaoude P., El-Solh AA. 2013
Continuous Positive Airway Pressure (CPAP) Treatment Reduces Mortality at the Population Level de Batlle, J; Bertran, S; Turino, C; Escarrabill, J; Sánchez-de-la-Torre, M; Woehrle, H; Barbé, F 2018
Cardiovascular mortality in obstructive sleep apnea in the elderly: role of long-term continuous positive airway pressure treatment: a prospective observational study. zzz_Martínez-García MA., Campos-Rodríguez F., Catalán-Serra P., Soler-Cataluña JJ., Almeida-Gonzalez C., De la Cruz Morón I., Durán-Cantolla J., Montserrat JM. 2012
Stroke and other cardiovascular events in patients with obstructive sleep apnea and the effect of continuous positive airway pressure. Schipper MH., Jellema K., Thomassen BJW., Alvarez-Estevez D., Verbraecken J., Rijsman RM. 2017
All-cause mortality from obstructive sleep apnea in male and female patients with and without continuous positive airway pressure treatment: a registry study with 10 years of follow-up. Jennum P., Tønnesen P., Ibsen R., Kjellberg J. 2015
Continuous positive airway pressure and survival of very elderly persons with moderate to severe obstructive sleep apnea. López-Padilla D., Alonso-Moralejo R., Martínez-García MÁ., De la Torre Carazo S., Díaz de Atauri MJ. 2016
A retrospective analysis of 4000 patients with obstructive sleep apnea in Okinawa, Japan Nakamura, H. and Kanemura, T. and Takara, C. and Tsukayama, A. and Tohyama, K. and Matsumoto, T. and Iseki, K. 2009
Incident Type 2 Diabetes in OSA and Effect of CPAP Treatment: A Retrospective Clinic Cohort Study. zzz_Xu PH., Hui CKM., Lui MMS., Lam DCL., Fong DYT., Ip MSM. 2019
Quality of life among untreated sleep apnea patients compared with the general population and changes after treatment with positive airway pressure. Bjornsdottir E., Keenan BT., Eysteinsdottir B., Arnardottir ES., Janson C., Gislason T., Sigurdsson JF., Kuna ST., Pack AI., Benediktsdottir B. 2015
Association of Continuous Positive Airway Pressure Treatment With Sexual Quality of Life in Patients With Sleep Apnea: Follow-up Study of a Randomized Clinical Trial. Jara SM., Hopp ML., Weaver EM. 2018
Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial. Barbé F., Durán-Cantolla J., Sánchez-de-la-Torre M., Martínez-Alonso M., Carmona C., Barceló A., Chiner E., Masa JF., Gonzalez M., Marín JM., Garcia-Rio F., Diaz de Atauri J., Terán J., Mayos M., de la Peña M., Monasterio C., del Campo F., Montserrat JM. 2012
Long-term effects of continuous positive airway pressure on blood pressure and prognosis in hypertensive patients with coronary heart disease and obstructive sleep apnea: a randomized controlled trial. Huang Z., Liu Z., Luo Q., Zhao Q., Zhao Z., Ma X., Liu W., Yang D. 2015
Effect of CPAP therapy on C-reactive protein and cognitive impairment in patients with obstructive sleep apnea hypopnea syndrome. Wu SQ., Liao QC., Xu XX., Sun L., Wang J., Chen R. 2016
CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea. McEvoy RD., Antic NA., Heeley E., Luo Y., Ou Q., Zhang X., Mediano O., Chen R., Drager LF., Liu Z., Chen G., Du B., McArdle N., Mukherjee S., Tripathi M., Billot L., Li Q., Lorenzi-Filho G., Barbe F., Redline S., Wang J., Arima H., Neal B., White DP., Grunstein RR., Zhong N., Anderson CS. 2016
Continuous positive airway pressure improves sleepiness but not calculated vascular risk in patients with minimally symptomatic obstructive sleep apnoea: the MOSAIC randomised controlled trial. Craig SE., Kohler M., Nicoll D., Bratton DJ., Nunn A., Davies R., Stradling J. 2012
Continuous positive airway pressure in older people with obstructive sleep apnoea syndrome (PREDICT): a 12-month, multicentre, randomised trial. McMillan A., Bratton DJ., Faria R., Laskawiec-Szkonter M., Griffin S., Davies RJ., Nunn AJ., Stradling JR., Riha RL., Morrell MJ. 2014
Oral appliance therapy versus nasal continuous positive airway pressure in obstructive sleep apnea: a randomized, placebo-controlled trial on psychological distress. Aarab G., Nikolopoulou M., Ahlberg J., Heymans MW., Hamburger HL., de Lange J., Lobbezoo F. 2017
Effects of continuous positive airway pressure on neurocognitive function in obstructive sleep apnea patients: The Apnea Positive Pressure Long-term Efficacy Study (APPLES). Kushida CA., Nichols DA., Holmes TH., Quan SF., Walsh JK., Gottlieb DJ., Simon RD., Guilleminault C., White DP., Goodwin JL., Schweitzer PK., Leary EB., Hyde PR., Hirshkowitz M., Green S., McEvoy LK., Chan C., Gevins A., Kay GG., Bloch DA., Crabtree T., Dement WC. 2012
Effect of Continuous Positive Airway Pressure Treatment on Health-Related Quality of Life and Sleepiness in High Cardiovascular Risk Individuals With Sleep Apnea: Best Apnea Interventions for Research (BestAIR) Trial. Zhao YY., Wang R., Gleason KJ., Lewis EF., Quan SF., Toth CM., Morrical M., Rueschman M., Weng J., Ware JH., Mittleman MA., Redline S. 2017
Continuous Positive Airway Pressure Treatment Reduces Mortality in Elderly Patients with Moderate to Severe Obstructive Severe Sleep Apnea: A Cohort Study. Ou Q., Chen YC., Zhuo SQ., Tian XT., He CH., Lu XL., Gao XL. 2015
Long-term oral appliance therapy in obstructive sleep apnea syndrome: a controlled study on temporomandibular side effects. Doff MH., Veldhuis SK., Hoekema A., Slater JJ., Wijkstra PJ., de Bont LG., Stegenga B. 2012
The Effect of Treatment of Obstructive Sleep Apnea on Glycemic Control in Type 2 Diabetes. Shaw JE., Punjabi NM., Naughton MT., Willes L., Bergenstal RM., Cistulli PA., Fulcher GR., Richards GN., Zimmet PZ. 2016
Evaluation of autoCPAP devices in home treatment of sleep apnea/hypopnea syndrome. Meurice JC., Cornette A., Philip-Joet F., Pepin JL., Escourrou P., Ingrand P., Veale D. 2007
Clinical- and Cost-Effectiveness of a Mandibular Advancement Device Versus Continuous Positive Airway Pressure in Moderate Obstructive Sleep Apnea. de Vries GE., Hoekema A., Vermeulen KM., Claessen JQPJ., Jacobs W., van der Maten J., van der Hoeven JH., Stegenga B., Kerstjens HAM., Wijkstra PJ. 2019
Positive airway pressure initiation: a randomized controlled trial to assess the impact of therapy mode and titration process on efficacy, adherence, and outcomes. Kushida CA., Berry RB., Blau A., Crabtree T., Fietze I., Kryger MH., Kuna ST., Pegram GV., Penzel T. 2011
Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. zzz_Marin JM., Carrizo SJ., Vicente E., Agusti AG. 2005
Long-term survival in veterans with sleep apnea Jara SM, Phipps AI , Maynard C, Weaver EM 2018
Obstructive sleep apnea as a risk factor for type 2 diabetes. Botros N., Concato J., Mohsenin V., Selim B., Doctor K., Yaggi HK. 2009
Protective Effect of Long-Term CPAP Therapy on Cognitive Performance in Elderly Patients with Severe OSA: The PROOF Study. Crawford-Achour E., Dauphinot V., Martin MS., Tardy M., Gonthier R., Barthelemy JC., Roche F. 2015
Predictors for Progression of Sleep Disordered Breathing among Public Transport Drivers: A 3-Year Follow-Up Study. Lin CY., Shih TS., Liou SH., Lin MH., Chang CP., Chou TC. 2015
Association of incident cardiovascular disease with progression of sleep-disordered breathing. zzz_Chami HA., Resnick HE., Quan SF., Gottlieb DJ. 2011
The role of daytime sleepiness in psychosocial outcomes after treatment for obstructive sleep apnea. Lau EY., Eskes GA., Morrison DL., Rajda M., Spurr KF. 2013
Conventional Polysomnography Is Not Necessary for the Management of Most Patients with Suspected Obstructive Sleep Apnea. Noninferiority, Randomized Controlled Trial. Corral J., Sánchez-Quiroga MÁ., Carmona-Bernal C., Sánchez-Armengol Á., de la Torre AS., Durán-Cantolla J., Egea CJ., Salord N., Monasterio C., Terán J., Alonso-Alvarez ML., Muñoz-Méndez J., Arias EM., Cabello M., Montserrat JM., De la Peña M., Serrano JC., Barbe F., Masa JF. 2017
Treatment of OSA reduces the risk of repeat revascularization after percutaneous coronary intervention. Wu X., Lv S., Yu X., Yao L., Mokhlesi B., Wei Y. 2015
Comparison of titrable thermoplastic versus custom-made mandibular advancement device for the treatment of obstructive sleep apnoea. Gagnadoux F., Nguyen XL., Le Vaillant M., Priou P., Meslier N., Eberlein A., Kun-Darbois JD., Chaufton C., Villiers B., Levy M., Trzépizur W., Launois S. 2017
Survival benefit of CPAP favors hypercapnic patients with the overlap syndrome. Jaoude P., Kufel T., El-Solh AA. 2014
Impact of an oral appliance on obstructive sleep apnea severity, quality of life, and biomarkers. Fernández-Julián E., Pérez-Carbonell T., Marco R., Pellicer V., Rodriguez-Borja E., Marco J. 2018
Longitudinal assessment of sleep disordered breathing in Vietnam veterans with post-traumatic stress disorder. zzz_Yesavage JA., Kinoshita LM., Noda A., Lazzeroni LC., Fairchild JK., Friedman L., Sekhon G., Thompson S., Cheng J., Zeitzer JM. 2014
Patient-reported outcome: results of the multicenter German post-market study. Hasselbacher K., Hofauer B., Maurer JT., Heiser C., Steffen A., Sommer JU. 2018
Improved cognitive functions after treatment with an oral appliance in obstructive sleep apnea. Tegelberg A., Wilhelmsson B., Erixon-Lindroth N., Lindström LH. 2012
A comparison of the long-term outcome and effects of surgery or continuous positive airway pressure on patients with obstructive sleep apnea syndrome. Lin SW., Chen NH., Li HY., Fang TJ., Huang CC., Tsai YH., Lee CH. 2006
A 7-year follow-up study of obstructive sleep apnoea in healthy elderly: The PROOF cohort study. Sforza E., Hupin D., Pichot V., Barthélémy JC., Roche F. 2017
OSA and Prognosis After Acute Cardiogenic Pulmonary Edema: The OSA-CARE Study. Uchôa CHG., Pedrosa RP., Javaheri S., Geovanini GR., Carvalho MMB., Torquatro ACS., Leite APDL., Gonzaga CC., Bertolami A., Amodeo C., Petisco ACGP., Barbosa JEM., Macedo TA., Bortolotto LA., Oliveira MT., Lorenzi-Filho G., Drager LF. 2017
Durability of treatment effects of the Sleep Position Trainer versus oral appliance therapy in positional OSA: 12-month follow-up of a randomized controlled trial. de Ruiter MHT., Benoist LBL., de Vries N., de Lange J. 2018
Adjustable thermoplastic mandibular advancement device for obstructive sleep apnea: outcomes and practicability. Banhiran W., Kittiphumwong P., Assanasen P., Chongkolwatana C., Metheetrairut C. 2014
Long-term changes of sexual function in men with obstructive sleep apnea after initiation of continuous positive airway pressure. Budweiser S., Luigart R., Jörres RA., Kollert F., Kleemann Y., Wieland WF., Pfeifer M., Arzt M. 2013
Upper Airway Stimulation for Obstructive Sleep Apnea: 5-Year Outcomes. Woodson BT., Strohl KP., Soose RJ., Gillespie MB., Maurer JT., de Vries N., Padhya TA., Badr MS., Lin HS., Vanderveken OM., Mickelson S., Strollo PJ. 2018
Long-Term Oral Appliance Therapy Improves Daytime Function and Mood in Upper Airway Resistance Syndrome Patients. Godoy LBM., Palombini L., Poyares D., Dal-Fabbro C., Guimarães TM., Klichouvicz PC., Tufik S., Togeiro SM. 2017
Prospective study of the association between sleep-disordered breathing and hypertension. Peppard PE., Young T., Palta M., Skatrud J. 2000
Effectiveness of continuous positive airway pressure in mild sleep apnea-hypopnea syndrome. Monasterio C., Vidal S., Duran J., Ferrer M., Carmona C., Barbé F., Mayos M., Gonzalez-Mangado N., Juncadella M., Navarro A., Barreira R., Capote F., Mayoralas LR., Peces-Barba G., Alonso J., Montserrat JM. 2001
Sleep Apnea, Cognitive Profile, and Vascular Changes: An Intriguing Relationship. zzz_Buratti L., Viticchi G., Baldinelli S., Falsetti L., Luzzi S., Pulcini A., Petrelli C., Provinciali L., Silvestrini M. 2017
CPAP therapy improves erectile function in patients with severe obstructive sleep apnea. Schulz R., Bischof F., Galetke W., Gall H., Heitmann J., Hetzenecker A., Laudenburg M., Magnus TJ., Nilius G., Priegnitz C., Randerath W., Schröder M., Treml M., Arzt M. 2019
Autoadjusted versus fixed CPAP for obstructive sleep apnoea: a multicentre, randomised equivalence trial. Bloch KE., Huber F., Furian M., Latshang TD., Lo Cascio CM., Nussbaumer-Ochsner Y., Senn O., Russi EW., Kohler M., Schoch OD., Turk A., Imhof E., Laube I., Matthews F., Thurnheer R. 2018
Sleep apnea and glucose metabolism: a long-term follow-up in a community-based sample. Lindberg E., Theorell-Haglöw J., Svensson M., Gislason T., Berne C., Janson C. 2012
Predictors of improvements in daytime function outcomes with CPAP therapy. Kingshott RN., Vennelle M., Hoy CJ., Engleman HM., Deary IJ., Douglas NJ. 2000
Long-term Effect of CPAP Treatment on Cardiovascular Events in Patients With Resistant Hypertension and Sleep Apnea. Data From the HIPARCO-2 Study. Navarro-Soriano C., Martínez-García MA., Torres G., Barbé F., Sánchez-de-la-Torre M., Caballero-Eraso C., Lloberes P., Cambriles TD., Somoza M., Masa JF., González M., Mañas E., de la Peña M., García-Río F., Montserrat JM., Muriel A., Oscullo G., García-Ortega A., Posadas T., Campos-Rodríguez F. 2021
Association of continuous positive airway pressure compliance with complications in patients with type 2 diabetes and obstructive sleep apnea. Sheth U., Monson RS., Prasad B., Sahni A., Matani S., Mercado T., Smith MA., Carlucci MA., Danielson KK., Reutrakul S. 2021
Continuous positive pressure therapy usage and incident stroke in patients with obstructive sleep apnea: A nationwide population-based cohort study. Chang ET., Chen W., Wang LY., Chen SF., Hsu CY., Shen YC. 2020
Health-Related Quality of Life and Sleep Quality after 12 Months of Treatment in Nonsevere Obstructive Sleep Apnea: A Randomized Clinical Trial with Continuous Positive Airway Pressure and Mandibular Advancement Splints. Berg LM., Ankjell TKS., Sun YQ., Trovik TA., Rikardsen OG., Sjögren A., Moen K., Hellem S., Bugten V. 2020
Effect of obstructive sleep apnoea and its treatment with continuous positive airway pressure on the prevalence of cardiovascular events in patients with acute coronary syndrome (ISAACC study): a randomised controlled trial. Sánchez-de-la-Torre M., Sánchez-de-la-Torre A., Bertran S., Abad J., Duran-Cantolla J., Cabriada V., Mediano O., Masdeu MJ., Alonso ML., Masa JF., Barceló A., de la Peña M., Mayos M., Coloma R., Montserrat JM., Chiner E., Perelló S., Rubinós G., Mínguez O., Pascual L., Cortijo A., Martínez D., Aldomà A., Dalmases M., McEvoy RD., Barbé F. 2020
Mortality in obstructive sleep apnea-hypopnea patients treated with positive airway pressure. Campos-Rodriguez F., Peña-Griñan N., Reyes-Nuñez N., De la Cruz-Moron I., Perez-Ronchel J., De la Vega-Gallardo F., Fernandez-Palacin A. 2005
Economic arguments for the immediate management of moderate-to-severe obstructive sleep apnoea syndrome. Pelletier-Fleury N., Meslier N., Gagnadoux F., Person C., Rakotonanahary D., Ouksel H., Fleury B., Racineux JL. 2004




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