Study Title and Description
Noninvasive vagus nerve stimulation as acute therapy for migraine: The randomized PRESTO study.
Key Questions Addressed
|3||KQ3a. What is the comparative effectiveness of nonpharmacologic therapy versus sham treatment, waitlist, usual care, attention control, and no treatment after followup at the following intervals: < 1 day; 1 day to <1 week; 1 week to <2 weeks; 2 weeks to 4 weeks? KQ3b. What is the comparative effectiveness of nonpharmacologic treatments (e.g. exercise, cognitive behavioral therapy, acupuncture, biofeedback, noninvasive neuromodulation devices) for outcomes related to pain, function, pain relief satisfaction, and quality of life? KQ3c. How does effectiveness of nonpharmacologic therapy vary depending on: (1) patient demographics (e.g. age, gender); (2) patient medical comorbidities? KQ3d. How do harms vary depending on: (1) patient demographics (e.g. age, gender); (2) patient medical comorbidities; (3) the type of treatment used; (4) the frequency of therapy; (5) the duration of therapy?|
Primary Publication Information
|Title||Noninvasive vagus nerve stimulation as acute therapy for migraine: The randomized PRESTO study.|
|Author||Tassorelli C., Grazzi L., de Tommaso M., Pierangeli G., Martelletti P., Rainero I., Dorlas S., Geppetti P., Ambrosini A., Sarchielli P., Liebler E., Barbanti P.|
|Country||From the Headache Science Centre (C.T.), IRCCS C. Mondino Foundation, Pavia; University of Pavia (C.T.); Headache Center (L.G.), Carlo Besta Neurological Institute and Foundation, Milan; Neurophysiology and Pain Unit (M.d.T.), University of Bari Aldo Moro; Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) (G.P.), Istituto delle Scienze Neurologiche di Bologna; Department of Clinical and Molecular Medicine (P.M.), Sapienza University, Rome; Department of Neuroscience (I.R.), University of Turin, Italy; MedLogix Communications, LLC (S.D.), Itasca IL; Headache Centre (P.G.), University Hospital of Careggi, Florence; IRCCS Neuromed (A.A.), Pozzilli (IS); Neurologic Clinic (P.S.), Santa Maria della Misericordia Hospital, Perugia, Italy; electroCore, LLC (E.L.), Basking Ridge, NJ; and Headache and Pain Unit (P.B.), IRCCS San Raffaele Pisana, Rome, Italy. firstname.lastname@example.org.|
Pubmed ID: 29907608
Secondary Publication Information
There are currently no secondary publications defined for this study.
Extraction Form: Key Question 3
|Question... Follow Up||Answer||Follow-up Answer|
Results & Comparisons
No Results found.