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Study Title and Description

Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B.



Key Questions Addressed
4 Key Question 4. How effective is antiviral treatment in improving intermediate outcomes among nonpregnant adolescents and adults with chronic HBV infection, including virologic or histologic improvement, clearance of hepatitis B e-antigen (HBeAg) (as indicated by loss of HBeAg or acquisition of the antibody to HBeAg [anti-HBe]), or clearance of hepatitis B surface antigen (HBsAg) (as indicated by loss of HBsAg or acquisition of hepatitis B surface antibody [anti-HBs])?
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5 Key Question 5. How effective is antiviral treatment in improving health outcomes among nonpregnant adolescents and adults with chronic HBV infection?
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6 Key Question 6. What are the harms associated with antiviral treatment in nonpregnant adolescents and adults with chronic HBV infection?
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Primary Publication Information
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TitleData
Title Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B.
Author Marcellin P., Heathcote EJ., Buti M., Gane E., de Man RA., Krastev Z., Germanidis G., Lee SS., Flisiak R., Kaita K., Manns M., Kotzev I., Tchernev K., Buggisch P., Weilert F., Kurdas OO., Shiffman ML., Trinh H., Washington MK., Sorbel J., Anderson J., Snow-Lampart A., Mondou E., Quinn J., Rousseau F.
Country Hôpital Beaujon, Assistance Publique Hôpitaux de Paris, University of Paris 7 and INSERM Unité 773, Centre de Recherches Claude Bernard sur les Hepatites Virales, Clichy, France.
Year 2008
Numbers Pubmed ID: 19052126

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Questions 1-7


Results & Comparisons

No Results found.