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Study Title and Description

Comparison of ImmunoCard Toxins A&B and the new semiautomated Vidas Clostridium difficile Toxin A&B tests for diagnosis of C. difficile infection.



Key Questions Addressed
1 Key Question 1 - Summary of matched comparisons of select assays for C. difficile toxins
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Primary Publication Information
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TitleData
Title Comparison of ImmunoCard Toxins A&B and the new semiautomated Vidas Clostridium difficile Toxin A&B tests for diagnosis of C. difficile infection.
Author Alcalá L., Marín M., Madrid M., Domínguez-García E., Catalán P., Peláez MT., Sánchez-Somolinos M., Bouza E.
Country -- Not Found --
Year 2010
Numbers Pubmed ID: 20071550

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Question 1 - Summary of matched comparisons of select assays for C. difficult toxins (Table C1)
Design Details
Question... Follow Up Answer Follow-up Answer
Patients/ Site n=412 Unknown suspected CDI Madrid, Spain Unknown spectrum Unknown selection
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Tested Specimens n= 487 Unknown fresh Unknown consistency Unknown blinded equivocal results were called negative
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Reference Standard/ % Positive in Sample CTA followed by toxigenic culture if negative 12.7%
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Tests Compared Premier ImmunoCard Toxins A&B, Meridian VIDAS C. difficile Tox A/B, bioMerieux
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PPV/ NPV Premier ImmunoCard Toxins A&B, Meridian PPV 42/63=66.7% NPV 404/424=95.3% VIDAS C. difficile Tox A/B, bioMerieux PPV 43/51=84.3% NPV 417/436=95.6%
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True Positive/ False Positive‡ Premier ImmunoCard Toxins A&B, Meridian True Positive 42/62=67.7% False Positive 21/425=4.9% VIDAS C. difficile Tox A/B, bioMerieux True Positive 43/62=69.4% False Positive 8/425=1.9%
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Results & Comparisons

No Results found.