Advanced Search

Study Preview



Study Title and Description

Diagnostic value of five commercial tests for the rapid diagnosis of Clostridium difficile-associated disease.



Key Questions Addressed
1 Key Question 1 - Summary of matched comparisons of select assays for C. difficile toxins
  • Comments Comments (
    0
    ) |

Primary Publication Information
  • Comments Comments (
    0
    ) |
TitleData
Title Diagnostic value of five commercial tests for the rapid diagnosis of Clostridium difficile-associated disease.
Author Miendje Deyi VY., Vandenberg O., Mascart G., Gning S., Retore P., Douat N., Dediste A.
Country Microbiology Department, Centre Hospitalier Universitaire Brugmann, Université Libre de Bruxelles, Brussels, Belgium. yvette.miendje@chu-brugmann.be
Year 2008
Numbers Pubmed ID: 18510038

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Question 1 - Summary of matched comparisons of select assays for C. difficult toxins (Table C1)
Design Details
Question... Follow Up Answer Follow-up Answer
Patients/ Site n=91 Age 65-99 avg. 81 yrs; suspected CDI; 2 university hospitals in Brussels, Belgium; 1 hospital had recent outbreak of C. difficile; Unknown spectrum Unknown selection
  • Comments Comments (
    0
    ) |
Tested Specimens n=100 frozen at -70o C; Unknown consistency tested blindly on same day in same lab Unknown indeterminate results
  • Comments Comments (
    0
    ) |
Reference Standard/ % Positive in Sample CTA 23.0%
  • Comments Comments (
    0
    ) |
Tests Compared ImmunoCard Toxins A&B, Meridian Xpect C. diff. toxin A/B, Remel TOX A/B QUIK CHEK, Techlab
  • Comments Comments (
    0
    ) |
PPV/ NPV ImmunoCard Toxins A&B, Meridian PPV 21/21=100% NPV 77/79=97.5% Xpect C. diff. toxin A/B, Remel PPV 21/21=100% NPV 77/79=97.5% TOX A/B QUIK CHEK, Techlab PPV 22/22=100% NPV 77/78=98.7%
  • Comments Comments (
    0
    ) |
True Positive/ False Positive‡ ImmunoCard Toxins A&B, Meridian True Positive 21/23=91.3% False Positive 0/77=0% Xpect C. diff. toxin A/B, Remel True Positive 21/23=91.3% False Positive 0/77=0% TOX A/B QUIK CHEK, Techlab True Positive 22/23=95.7% False Positive 0/77=0%
  • Comments Comments (
    0
    ) |




Results & Comparisons

No Results found.