Study Title and Description
Evaluation of two rapid immunochromatography tests for the detection of Clostridium difficile toxins.
Key Questions Addressed
|1||Key Question 1 - Summary of matched comparisons of select assays for C. difficile toxins|
Primary Publication Information
|Title||Evaluation of two rapid immunochromatography tests for the detection of Clostridium difficile toxins.|
|Author||Samra Z., Luzon A., Bishara J.|
|Country||Department of Clinical Microbiology, Rabin Medical Center, Beilinson Hospital, Petah Tiqwa, Israel.|
Pubmed ID: 17990108
Secondary Publication Information
There are currently no secondary publications defined for this study.
Extraction Form: Key Question 1 - Summary of matched comparisons of select assays for C. difficult toxins (Table C1)
|Question... Follow Up||Answer||Follow-up Answer|
|Patients/ Site||n=200 hospitalized patients with diarrhea; Rabin Medical Center, Israel Unknown spectrum Unknown selection|
|Tested Specimens||n= 200 fresh or refrigerated diarrhea; randomly selected from positive and negative results; Unknown blinded Unknown indeterminate results|
|Reference Standard/ % Positive in Sample||In-house PCR for toxin B gene 47.0%|
|Tests Compared||Tox A/B II, Techlab Tox A/B Quik Chek, Techlab Immmunocard Toxin A&B, Meridian|
|PPV/ NPV||Tox A/B II, Techlab PPV 88/94=93.6% NPV 100/106=94.3% Tox A/B Quik Chek, Techlab PPV 89/92=96.7% NPV 103/108=95.4% Immmunocard Toxin A&B, Meridian PPV 89/92=96.7% NPV 103/108=95.4%|
|True Positive/ False Positive‡||Tox A/B II, Techlab True Positive 88/94=93.6% False Positive 6/106=5.7% Tox A/B Quik Chek, Techlab True Positive 89/94=94.7% False Positive 3/106=2.8% Immmunocard Toxin A&B, Meridian True Positive 89/94=94.7% False Positive 3/106=2.8%|
Results & Comparisons
No Results found.