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Study Title and Description

Evaluation of two rapid immunochromatography tests for the detection of Clostridium difficile toxins.



Key Questions Addressed
1 Key Question 1 - Summary of matched comparisons of select assays for C. difficile toxins
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Primary Publication Information
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TitleData
Title Evaluation of two rapid immunochromatography tests for the detection of Clostridium difficile toxins.
Author Samra Z., Luzon A., Bishara J.
Country Department of Clinical Microbiology, Rabin Medical Center, Beilinson Hospital, Petah Tiqwa, Israel.
Year 2008
Numbers Pubmed ID: 17990108

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Question 1 - Summary of matched comparisons of select assays for C. difficult toxins (Table C1)
Design Details
Question... Follow Up Answer Follow-up Answer
Patients/ Site n=200 hospitalized patients with diarrhea; Rabin Medical Center, Israel Unknown spectrum Unknown selection
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Tested Specimens n= 200 fresh or refrigerated diarrhea; randomly selected from positive and negative results; Unknown blinded Unknown indeterminate results
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Reference Standard/ % Positive in Sample In-house PCR for toxin B gene 47.0%
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Tests Compared Tox A/B II, Techlab Tox A/B Quik Chek, Techlab Immmunocard Toxin A&B, Meridian
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PPV/ NPV Tox A/B II, Techlab PPV 88/94=93.6% NPV 100/106=94.3% Tox A/B Quik Chek, Techlab PPV 89/92=96.7% NPV 103/108=95.4% Immmunocard Toxin A&B, Meridian PPV 89/92=96.7% NPV 103/108=95.4%
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True Positive/ False Positive‡ Tox A/B II, Techlab True Positive 88/94=93.6% False Positive 6/106=5.7% Tox A/B Quik Chek, Techlab True Positive 89/94=94.7% False Positive 3/106=2.8% Immmunocard Toxin A&B, Meridian True Positive 89/94=94.7% False Positive 3/106=2.8%
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Results & Comparisons

No Results found.