Study Title and Description
Evaluation of methods for detection of toxins in specimens of feces submitted for diagnosis of Clostridium difficile-associated diarrhea.
Key Questions Addressed
|1||Key Question 1 - Summary of matched comparisons of select assays for C. difficile toxins|
Primary Publication Information
|Title||Evaluation of methods for detection of toxins in specimens of feces submitted for diagnosis of Clostridium difficile-associated diarrhea.|
|Author||O'Connor D., Hynes P., Cormican M., Collins E., Corbett-Feeney G., Cassidy M.|
|Country||Microbiology Laboratory, Portiuncula Hospital, Ballinasloe, County Galway, Galway, Ireland. email@example.com|
Pubmed ID: 11474001
Secondary Publication Information
There are currently no secondary publications defined for this study.
Extraction Form: Key Question 1 - Summary of matched comparisons of select assays for C. difficult toxins (Table C1)
|Question... Follow Up||Answer||Follow-up Answer|
|Patients/ Site||n=133 Adults, consecutive samples, CDI suspected; Multiple health centers in Galway County area of Ireland Unknown spectrum Unknown selection|
|Tested Specimens||n=200 92% liquid or unformed; -20o C for CTA, then frozen at 84o C; Unknown blinded|
|Reference Standard/ % Positive in Sample||CTA 30.5%|
|Tests Compared||Premier Toxins A&B, Meridian C. diff Tox A/B II, Techlab|
|PPV/ NPV||Premier Toxins A&B, Meridian PPV 50/51=98.0% NPV 138/149=92.6% C. diff Tox A/B II, Techlab PPV 49/50=98.0% NPV 138/150=92.0%|
|True Positive/ False Positive‡||Premier Toxins A&B, Meridian True Positive 50/61=82.0% False Positive 1/139=0.7% C. diff Tox A/B II, Techlab True Positive 49/61=80.3% False Positive 1/139=0.7%|
Results & Comparisons
No Results found.