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Study Title and Description

Emergence and control of fluoroquinolone-resistant, toxin A-negative, toxin B-positive Clostridium difficile.



Key Questions Addressed
3 Key Question 3 - Prevention interventions
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4 Key Question 4 - Studies of Multiple Interventions used together to reduce CDI incidence
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Primary Publication Information
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TitleData
Title Emergence and control of fluoroquinolone-resistant, toxin A-negative, toxin B-positive Clostridium difficile.
Author Drudy D., Harnedy N., Fanning S., Hannan M., Kyne L.
Country Centre for Food Safety, School of Agriculture, University College, Dublin, Ireland.
Year 2007
Numbers Pubmed ID: 17620240

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Question 2 - Prevention interventions (Table 4)
Design Details
Question... Follow Up Answer Follow-up Answer
Country Ireland
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Study Design Prospective time series (before-after)
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Population Hospital patients
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Category of Intervention Multiple Interventions
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Intervention Antimicrobial use, enhanced surveillance, education, hand hygiene, equipment, intensified environmental cleaning
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Outcome CDI incidence
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Findings CDI incidence decreased from a peak of 21 cases/1,000 patient admissions to 5/1,000 patient admissions
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Quality Issues No concurrent controls
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Results & Comparisons

No Results found.

Extraction Form: Key Question 2 - Studies of Multiple Interventions used together to reduce CDI incidence (Tables 5, 6)
Arms
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Design Details
Question... Follow Up Answer Follow-up Answer
Type of Study Prospect time series (before–after)
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Epidemic or Excessive Incidence? Yes
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CDI incidence Decreased After intervention? Yes
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Results & Comparisons

No Results found.

Quality Dimensions
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Quality Rating
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