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Study Title and Description

Decrease in nosocomial Clostridium difficile-associated diarrhea by restricting clindamycin use.



Key Questions Addressed
3 Key Question 3 - Prevention interventions
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4 Key Question 4 - Studies of Multiple Interventions used together to reduce CDI incidence
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Primary Publication Information
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TitleData
Title Decrease in nosocomial Clostridium difficile-associated diarrhea by restricting clindamycin use.
Author Pear SM., Williamson TH., Bettin KM., Gerding DN., Galgiani JN.
Country Veterans Affairs Medical Center, Tucson, AZ.
Year 1994
Numbers Pubmed ID: 8080497

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Question 2 - Prevention interventions (Table 4)
Design Details
Question... Follow Up Answer Follow-up Answer
Country USA
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Study Design Prospective time series (before-after)
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Population Hospital patients (Veterans Affairs)
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Category of Intervention Multiple Interventions
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Intervention Antimicrobial use, education, isolation, patient room practices, intensified environmental cleaning
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Outcome CDI incidence
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Findings Nosocomial epidemic of CDI was controlled by analysis of antibiotic use patterns and by subsequent restriction of clindamycin
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Quality Issues No concurrent controls
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Results & Comparisons

No Results found.

Extraction Form: Key Question 2 - Studies of Multiple Interventions used together to reduce CDI incidence (Tables 5, 6)
Arms
No arms have been defined in this extraction form.

Design Details
Question... Follow Up Answer Follow-up Answer
Type of Study Prospect time series (before–after)
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Epidemic or Excessive Incidence? Yes
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CDI incidence Decreased After intervention? Yes
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Results & Comparisons

No Results found.

Quality Dimensions
No quality dimensions were specified.

Quality Rating
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