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Study Title and Description

Systemic absorption of oral cholestyramine.



Key Questions Addressed
8 Key Question 8 - Case studies/series and potential harms of nonstandard interventions for CDI
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Primary Publication Information
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TitleData
Title Systemic absorption of oral cholestyramine.
Author McDonald GB., Vracko R.
Country -- Not Found --
Year 1984
Numbers Pubmed ID: 6724264
1427 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Question 4 - Case studies/series and potential harms of nonstandard interventions for CDI (Table C11)
Design Details
Question... Follow Up Answer Follow-up Answer
Study Focus Treatment
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Subject/Study Details Male, age 76 years Tx for diarrhea and PSC per sigmoidoscopy
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Interventions Cholestyramine (toxin absorbing resin) 12 grams(g)/day (d)orally
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Clinical Diarrhea Outcomes pseudomembranous colitis resolved at autopsy
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C. difficile Toxin, C. difficile Culture, or Other C. difficile toxin + stools for 1 month after symptomatic relief C. difficile culture + stools for 1 month
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Adverse Effects (AE) Harms Cholestyramine particles in arterial and venous vessel walls at autopsy Ulcerated esophagus was likely portal
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Results & Comparisons

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