Advanced Search

Study Preview



Study Title and Description

Effects of combination therapy with direct hemoperfusion using polymyxin B-immobilized fiber and oral vancomycin on fulminant pseudomembranous colitis with septic shock.



Key Questions Addressed
8 Key Question 8 - Case studies/series and potential harms of nonstandard interventions for CDI
  • Comments Comments (
    0
    ) |

Primary Publication Information
  • Comments Comments (
    0
    ) |
TitleData
Title Effects of combination therapy with direct hemoperfusion using polymyxin B-immobilized fiber and oral vancomycin on fulminant pseudomembranous colitis with septic shock.
Author Kimura Y., Sato K., Tokuda H., Nakamura N., Dohi Y., Orito E., Mizokami M.
Country Department of Internal Medicine, Nagoya City Johoku Hospital, 2-15 Kaneda-cho, Kita-ku, Nagoya 462-0033, Japan. yk3141@yahoo.co.jp
Year 2007
Numbers Pubmed ID: 17273924
1429 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Question 4 - Case studies/series and potential harms of nonstandard interventions for CDI (Table C11)
Design Details
Question... Follow Up Answer Follow-up Answer
Study Focus Treatment
  • Comments Comments (
    0
    ) |
Subject/Study Details 2 men, age 71 and 54 years with pseudomembranous colitis by colonoscopy, C. difficile toxin A and septic shock
  • Comments Comments (
    0
    ) |
Interventions IV "hemoperfusion" agent: Vancomycin (2 g/d) orally + polymixin B- intramuscularmobilized fiber 80- 100 mg/d IV x 7-14 days
  • Comments Comments (
    0
    ) |
Clinical Diarrhea Outcomes
  • Comments Comments (
    0
    ) |
C. difficile Toxin, C. difficile Culture, or Other C. difficile toxin became negative after 7 days pseudomembranous colitis resolved after 7 days
  • Comments Comments (
    0
    ) |
Adverse Effects (AE) Harms Not reported
  • Comments Comments (
    0
    ) |




Results & Comparisons

No Results found.