Advanced Search

Study Preview



Study Title and Description

Faecal transplant for recurrent Clostridium difficile-associated diarrhoea: a UK case series.



Key Questions Addressed
8 Key Question 8 - Case studies/series and potential harms of nonstandard interventions for CDI
  • Comments Comments (
    0
    ) |

Primary Publication Information
  • Comments Comments (
    0
    ) |
TitleData
Title Faecal transplant for recurrent Clostridium difficile-associated diarrhoea: a UK case series.
Author MacConnachie AA., Fox R., Kennedy DR., Seaton RA.
Country Brownlee Centre, Gartnavel General Hospital, 1053 Great Western Road, Glasgow G12 0YN, UK. alisdair.macconnachie@ggc.scot.nhs.uk
Year 2009
Numbers Pubmed ID: 19726581
1432 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Question 4 - Case studies/series and potential harms of nonstandard interventions for CDI (Table C11)
Design Details
Question... Follow Up Answer Follow-up Answer
Study Focus Treatment for recurrent C. difficile infection
  • Comments Comments (
    0
    ) |
Subject/Study Details 15 patients with recurrent C. difficile infection which was defined as relapse of loose stool following antibiotic treatment for C. difficile toxin positive stool 14 females, age = 81.5 (68-95) years (median [range]) 11 were inpatients and 4 were newly readmitted after recent discharge; all had several comorbidities and were seriously ill Retrospective chart review
  • Comments Comments (
    0
    ) |
Interventions Fecal flora reconstitution: Stool from healthy relatives administered by nasogastric tube Donors were administered a proton pump inhibitor and oral vancomycin (125 mg 4 tintramusculares/d) up to 12 hours prior to reconstitution
  • Comments Comments (
    0
    ) |
Clinical Diarrhea Outcomes 11 (73%) with diarrhea were symptom free of diarrhea at followup and 4 had a relapse of diarrhea Followup was at 16 (4- 24) weeks (median [range])
  • Comments Comments (
    0
    ) |
C. difficile Toxin, C. difficile Culture, or Other
  • Comments Comments (
    0
    ) |
Adverse Effects (AE) Harms Reported as none
  • Comments Comments (
    0
    ) |




Results & Comparisons

No Results found.