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Study Title and Description

Fecal flora reconstitution for recurrent Clostridium difficile infection: results and methodology.



Key Questions Addressed
8 Key Question 8 - Case studies/series and potential harms of nonstandard interventions for CDI
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Primary Publication Information
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TitleData
Title Fecal flora reconstitution for recurrent Clostridium difficile infection: results and methodology.
Author Rohlke F., Surawicz CM., Stollman N.
Country Northern California Gastroenterology Consultants, Oakland, CA 94609, USA.
Year 2010
Numbers Pubmed ID: 20485184
1433 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Question 4 - Case studies/series and potential harms of nonstandard interventions for CDI (Table C11)
Design Details
Question... Follow Up Answer Follow-up Answer
Study Focus Treatment for recurrent C. difficile infection
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Subject/Study Details 19 patients with recurrent C. difficile infection defined as C. difficile toxin positivity and symptoms after at least 3 courses of antibiotic treatment 17 females, mean age = 49 years
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Interventions Fecal flora reconstitution: Stool from healthy relatives, partners, or housemates administered via colonoscopy
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Clinical Diarrhea Outcomes 18 (95%) became free of symptoms after initial treatment for 6-60 mos. 3 (17%) redeveloped symptoms after 6-48 mos.
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C. difficile Toxin, C. difficile Culture, or Other
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Adverse Effects (AE) Harms Not reported
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Results & Comparisons

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