Study Title and Description
Success of self-administered home fecal transplantation for chronic Clostridium difficile infection.
Key Questions Addressed
|8||Key Question 8 - Case studies/series and potential harms of nonstandard interventions for CDI|
Primary Publication Information
|Title||Success of self-administered home fecal transplantation for chronic Clostridium difficile infection.|
|Author||Silverman MS., Davis I., Pillai DR.|
|Country||Department of Medicine, University of Toronto, Toronto, Ontario, Canada. email@example.com|
Pubmed ID: 20117243
Secondary Publication Information
There are currently no secondary publications defined for this study.
Extraction Form: Key Question 4 - Case studies/series and potential harms of nonstandard interventions for CDI (Table C11)
|Question... Follow Up||Answer||Follow-up Answer|
|Study Focus||Treatment for recurrent C. difficile infection|
|Subject/Study Details||7 patients recurrent C. difficile infection defined as with diarrhea after a positive stool toxin test and antibiotic treatment 50% females, age range = 30-88 years; all lived at home after developing C. difficile infection in hospital Patients were treated with a standard antibiotic and probiotic (S. boulardii) up to 24- 48 hours before procedure|
|Interventions||Fecal flora reconstitution: Donor stools from relatives were infused by low-volume enema by self or family member|
|Clinical Diarrhea Outcomes||7 (100%) were free of diarrhea for up to 14 mos. followup|
|C. difficile Toxin, C. difficile Culture, or Other|
|Adverse Effects (AE) Harms||One patient developed infectious irritable bowel symptoms (alternating constipation and diarrhea) but C. difficile toxin test was negative|
Results & Comparisons
No Results found.