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Study Title and Description

Saccharomyces cerevisiae fungemia: an emerging infectious disease.



Key Questions Addressed
8 Key Question 8 - Case studies/series and potential harms of nonstandard interventions for CDI
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Primary Publication Information
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TitleData
Title Saccharomyces cerevisiae fungemia: an emerging infectious disease.
Author Muñoz P., Bouza E., Cuenca-Estrella M., Eiros JM., Pérez MJ., Sánchez-Somolinos M., Rincón C., Hortal J., Peláez T.
Country Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Universidad Complutense, Madrid, Spain. pmunoz@micro.hggm.es
Year 2005
Numbers Pubmed ID: 15889360
1438 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Key Question 4 - Case studies/series and potential harms of nonstandard interventions for CDI (Table C11)
Design Details
Question... Follow Up Answer Follow-up Answer
Study Focus Treatment
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Subject/Study Details Case studies + Retrospective chart review of ICU pts + review of 57 patients literature review. 3 ICU patients 3 ICU patients (females in 70s) with S. cerevisiae fungemia Charts of 41 (with 14 ICU) patients over 1 month of fungemia outbreak were reviewed
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Interventions Probiotic: 3 cases were treated with Ultralevura for C. difficile infection 2/41 patients without fungemia received probiotic
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Clinical Diarrhea Outcomes
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C. difficile Toxin, C. difficile Culture, or Other Probiotic cultures grew heavy yeast (>1 million cfu/ml) Mortality: 28% (17/60)
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Adverse Effects (AE) Harms 60 patients total with fungemia, 28/47 (60%) in ICU, 26 (46%) were treated with the probiotic
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Results & Comparisons

No Results found.