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Study Title and Description

Meta-analysis to assess risk factors for recurrent Clostridium difficile infection.



Key Questions Addressed
10 Key Question 10 - Reviews and Meta-analyses
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Primary Publication Information
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TitleData
Title Meta-analysis to assess risk factors for recurrent Clostridium difficile infection.
Author Garey KW., Sethi S., Yadav Y., DuPont HL.
Country University of Houston College of Pharmacy, Houston, TX 77030, USA. kgarey@uh.edu
Year 2008
Numbers Pubmed ID: 18951661
1490 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Reviews and Meta-analyses (Table C12)
Arms
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Design Details
Question... Follow Up Answer Follow-up Answer
Focus of Review Prevention
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Title/Question Patient Population Assess risk factors for recurrent CDI Adult inpatients
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# of Studies Patient N 3 RCT, 9 observational Meta-analysis
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Comparators Patients with recurrent versus patients with one episode only.
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Outcomes Followup Studies generally 1 to 3 months
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Results Continued use of non-C. difficile antibiotics after CDI diagnosis: OR 4.23 (2.10-8.55), use of antacid medication: OR 2.15 (1.13- 4.08), older age: OR 1.62 (1.11 - 2.36). (Many risk factors not included in analysis due to limited literature.)
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Baseline Characteristics
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Results & Comparisons

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Adverse Events
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