Study Title and Description
Systematic review of the risk of enteric infection in patients taking acid suppression.
Key Questions Addressed
|10||Key Question 10 - Reviews and Meta-analyses|
Primary Publication Information
|Title||Systematic review of the risk of enteric infection in patients taking acid suppression.|
|Author||Leonard J., Marshall JK., Moayyedi P.|
|Country||Department of Medicine, Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada.|
Pubmed ID: 17509031
Secondary Publication Information
There are currently no secondary publications defined for this study.
Extraction Form: Reviews and Meta-analyses (Table C12)
No arms have been defined in this extraction form.
|Question... Follow Up||Answer||Follow-up Answer|
|Focus of Review||Prevention|
|Title/Question Patient Population||Risk of enteric infection in patients taking acid suppression Primarily inpatient|
|# of Studies Patient N||25 observational studies N=1,382 Meta-analysis|
|Comparators||Use of PPI or H2RA versus multiple control group types|
|Outcomes Followup||Presence of enteric infection|
|Results||PPI: OR 2.05 (1.47-2.85); H2RA: OR 1.48 (1.06 - 2.06); Overall: OR 1.95 (1.48- 2.58). Significant heterogeneity between studies. ORs for other enteric infections were even greater. Index cases?|
No baseline characteristics have been defined for this extraction form.
Results & Comparisons
No Results found.
|Arm or Total||Title||Description||Comments|
No quality dimensions were specified.
No quality rating data was found.