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Study Title and Description

Antimotility agents for the treatment of Clostridium difficile diarrhea and colitis.



Key Questions Addressed
10 Key Question 10 - Reviews and Meta-analyses
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Primary Publication Information
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TitleData
Title Antimotility agents for the treatment of Clostridium difficile diarrhea and colitis.
Author Koo HL., Koo DC., Musher DM., DuPont HL.
Country Department of Medicine, Division of Infectious Diseases, Baylor College of Medicine, Houston, TX 77030, USA. koo@bcm.tmc.edu
Year 2009
Numbers Pubmed ID: 19191646
1493 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Reviews and Meta-analyses (Table C12)
Arms
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Design Details
Question... Follow Up Answer Follow-up Answer
Focus of Review Treatment
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Title/Question Patient Population Antimotility agents for CDI treatment Adult inpatients
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# of Studies Patient N 1 retrospective 19 case reports/series N = 55
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Comparators With or without antibiotic use
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Outcomes Followup Adverse events, clinical resolution
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Results All patients with documented complications or mortality received antimotility drugs alone initially. 23 patients who received concurrent antibiotics did not experience complications. (Use of antimotility did not appear to shorten disease course in the 23 patients.)
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Baseline Characteristics
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Results & Comparisons

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Adverse Events
Arm or Total Title Description Comments

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