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Study Title and Description

Antibiotic treatment for Clostridium difficile-associated diarrhea in adults.



Key Questions Addressed
10 Key Question 10 - Reviews and Meta-analyses
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Primary Publication Information
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TitleData
Title Antibiotic treatment for Clostridium difficile-associated diarrhea in adults.
Author Bricker E., Garg R., Nelson R., Loza A., Novak T., Hansen J.
Country -- Not Found --
Year 2005
Numbers Pubmed ID: 15674956
1499 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Reviews and Meta-analyses (Table C12)
Arms
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Design Details
Question... Follow Up Answer Follow-up Answer
Focus of Review Treatment
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Title/Question Patient Population Antibiotic treatment for C. difficile-associated diarrhea (and need for stopping causative) in adults Inpatients
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# of Studies Patient N 12 trials Meta-analysis
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Comparators 8 antibiotics, 1 placebo controlled
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Outcomes Followup Resolution/ negative tests, recurrence/ positive tests, surgery, death
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Results No single antibiotic clearly superior; teicoplanin showed some benefits over vancomycin, fusidic acid, metronidazole. Mild cases may be self-limiting without treatment. For prevention of spread, teicoplanin showed best bacteriologic cure.
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Baseline Characteristics
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Results & Comparisons

No Results found.
Adverse Events
Arm or Total Title Description Comments

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