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Study Title and Description

Intake of fish and n3 fatty acids and risk of coronary heart disease among Japanese: the Japan Public Health Center-Based (JPHC) Study Cohort I.



Key Questions Addressed
2 Observational studies (longitudinal; quantile or continuous analysis)
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Primary Publication Information
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TitleData
Title Intake of fish and n3 fatty acids and risk of coronary heart disease among Japanese: the Japan Public Health Center-Based (JPHC) Study Cohort I.
Author Iso H., Kobayashi M., Ishihara J., Sasaki S., Okada K., Kita Y., Kokubo Y., Tsugane S.
Country Department of Public Health Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki-ken, Japan. iso@phel.med.osaka-u.ac.jp
Year 2006
Numbers Pubmed ID: 16401768
545977 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Observational Studies
Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Observational: Prospective, longitudinal study of intake (eg, FFQ, biomarker)
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What is the name of this study? (e.g. DART, Physician's Health Study) Japan Public Health Center-Based (JPHC) Study - Cohort I
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Country in which study conducted (where subjects live) Japan
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Funding source No industry relationship reported (funding or affiliations reported)
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Eligibility Criteria: Men and women who were born between 1930 and 1949 (40 to 59 years of age) and who were registered in 14 administrative districts supervised by 4 public health center (PHC) areas on January 1, 1990. We excluded men who reported myocardial infarction, anginapectoris, stroke, or cancer at baseline.
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Study Population Primary Prevention, Healthy
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Conflict of interest No Data regarding conflict of interest
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Does the study report a subgroup or predictor (regression) analysis for an outcome of interest? No
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What type(s) of analysis is/are reported? Baseline intake (eg, from FFQ) vs. outcomes
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Quantiles of baseline measures
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Study start date(s) January 1, 1990
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Male, percent 48
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Dropouts, withdrawals, etc. 11349
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54498
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20.8
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did not complete baseline questionnaire
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Baseline characteristics, continuous 49
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Baseline Diseases/Conditions 4
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4
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16
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n3 Source Fish diet
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Results & Comparisons

No Results found.

Quality Dimensions
Dimension Value Notes Comments
Selection bias (NOT NESTED CASE CONTROL): Is there clear demonstration that the outcome of interest was not present at the start of the study (baseline)? Yes
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Comparability/Adjustment (ALL OBSERVATIONAL STUDIES): Were the analyses adjusted for confounders (or other factors)? Yes Including diet and CVD risk factors
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Outcome assessment (ALL STUDIES): Were OUTCOME ASSESSORS adequately BLINDED? Yes
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Incomplete outcome data (attrition bias) due to amount, nature or handling of incomplete outcome data (ALL STUDIES) LOW
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Nutrition, FFQ Baseline intake: Was the dietary assessment instrument (eg, FFQ) described to have measured n-3 FA (ALL STUDIES WITH FFQ)? Yes Measured n-3 FA from ONLY diet
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Nutrition, Baseline data: Were the ranges or distributions of the nutrient exposures adequately reported (ie, quantile means/medians SD and/or ranges) (ALL OBSERVATIONAL STUDIES)? No only mean within quantile reported
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Additional Bias: Bias due to problems not covered elsewhere in the table.
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Do any specific outcomes have a high risk of bias (different than others)? If so, describe in Notes.
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Quality Rating
No quality rating data was found.