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Study Title and Description

Fish, omega-3 polyunsaturated fatty acids, and mortality from cardiovascular diseases in a nationwide community-based cohort of Japanese men and women the JACC (Japan Collaborative Cohort Study for Evaluation of Cancer Risk) Study.



Key Questions Addressed
2 Observational studies (longitudinal; quantile or continuous analysis)
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Primary Publication Information
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TitleData
Title Fish, omega-3 polyunsaturated fatty acids, and mortality from cardiovascular diseases in a nationwide community-based cohort of Japanese men and women the JACC (Japan Collaborative Cohort Study for Evaluation of Cancer Risk) Study.
Author Yamagishi K., Iso H., Date C., Fukui M., Wakai K., Kikuchi S., Inaba Y., Tanabe N., Tamakoshi A.
Country Department of Public Health Medicine, Graduate School of Comprehensive Human Sciences, and Institute of Community Medicine, University of Tsukuba, Tsukuba, Japan.
Year 2008
Numbers Pubmed ID: 18786479

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Observational Studies
Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Observational: Prospective, longitudinal study of intake (eg, FFQ, biomarker)
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What is the name of this study? (e.g. DART, Physician's Health Study) JACC
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Country in which study conducted (where subjects live) Japan
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Funding source No industry relationship reported (funding or affiliations reported)
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Eligibility Criteria: Nationwide community-based sample; 40-79 years old; no history of heart disease/stroke/cancer at baseline; completed fish intake on FFQ
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Study Population Primary Prevention, Healthy
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Conflict of interest No Data regarding conflict of interest
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Does the study report a subgroup or predictor (regression) analysis for an outcome of interest? No
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What type(s) of analysis is/are reported? Baseline intake (eg, from FFQ) vs. outcomes
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Quantiles of baseline measures
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Study start date(s) 1988-1990
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Male, percent 39.5%
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Race 100
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not explicitly stated but study set in Japan
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Comments about quantiles. The baseline demographic and medical history characteristics given are for those in the middle quintile of fish intake, by sex
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Baseline characteristics, continuous 55.7 (men) 55.7 (women)
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22.7 (men) 22.9 (women)
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Baseline Diseases/Conditions 6 (men) 3 (women)
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18 (men) 19 (women)
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n3 Source Fish diet
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Results & Comparisons

No Results found.

Quality Dimensions
Dimension Value Notes Comments
Selection bias (NOT NESTED CASE CONTROL): Is there clear demonstration that the outcome of interest was not present at the start of the study (baseline)? Yes
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Comparability/Adjustment (ALL OBSERVATIONAL STUDIES): Were the analyses adjusted for confounders (or other factors)? Yes
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Outcome assessment (ALL STUDIES): Were OUTCOME ASSESSORS adequately BLINDED? Unsure
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Incomplete outcome data (attrition bias) due to amount, nature or handling of incomplete outcome data (ALL STUDIES) Yes 'We excluded persons who... were missing the fresh fish item, with more than 1 item missing from the other 3 fish items, or with more than 4 missing items from the 33 items on the dietary questionnaire.' ~1/2 of eligible men and women in their sample were excluded this way.
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Nutrition, FFQ Baseline intake: Was the dietary assessment instrument (eg, FFQ) described to have measured n-3 FA (ALL STUDIES WITH FFQ)? Yes diet only
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Nutrition, Baseline data: Were the ranges or distributions of the nutrient exposures adequately reported (ie, quantile means/medians SD and/or ranges) (ALL OBSERVATIONAL STUDIES)? Yes
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Additional Bias: Bias due to problems not covered elsewhere in the table.
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Do any specific outcomes have a high risk of bias (different than others)? If so, describe in Notes.
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Quality Rating
No quality rating data was found.