This is the old version of SRDR. The next, SRDRplus is available! Registration of your SRDRPlus account is free and approval is automatic. Click Here to register an SRDRPlus account.

Advanced Search

Study Preview



Study Title and Description

Relationships between plasma fatty acid composition and coronary artery disease.



Key Questions Addressed
2 Observational studies (longitudinal; quantile or continuous analysis)
  • Comments Comments (
    0
    ) |

Primary Publication Information
  • Comments Comments (
    0
    ) |
TitleData
Title Relationships between plasma fatty acid composition and coronary artery disease.
Author Itakura H., Yokoyama M., Matsuzaki M., Saito Y., Origasa H., Ishikawa Y., Oikawa S., Sasaki J., Hishida H., Kita T., Kitabatake A., Nakaya N., Sakata T., Shimada K., Shirato K., Matsuzawa Y.
Country Shinagawa East One Medical Clinic, Tokyo, Japan. shinagawa-east-one@jouzenkai.or.jp
Year 2011
Numbers Pubmed ID: 21099130

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Observational Studies
Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Observational: Prospective, longitudinal study of intake (eg, FFQ, biomarker)
  • Comments Comments (
    0
    ) |
What is the name of this study? (e.g. DART, Physician's Health Study) JELIS
  • Comments Comments (
    0
    ) |
Country in which study conducted (where subjects live) Japan
  • Comments Comments (
    0
    ) |
Funding source Industry only donated materials (eg, supplements)
  • Comments Comments (
    0
    ) |
Authors report industry affiliation
  • Comments Comments (
    0
    ) |
Eligibility Criteria: Hypercholesterolemia >250mg/dL total cholesterol or >170mg/dL LDL; everyone was on a statin (10mg pravastatin or 5mg simvastatin qd)
  • Comments Comments (
    0
    ) |
Study Population Primary Prevention, Increased CVD Risk (ie, diabetes, metabolic syndrome*, hypertension, dyslipidemia, or chronic kidney disease)
  • Comments Comments (
    0
    ) |
At baseline, did all subjects have (per eligibility criteria)...? ... Define: Dyslipidemia ... >250mg/dL total cholesterol or >170mg/dL LDL
  • Comments Comments (
    0
    ) |
Conflict of interest ... Specify Conflict of interest stated ... travel to scientific meeting
  • Comments Comments (
    0
    ) |
Does the study report a subgroup or predictor (regression) analysis for an outcome of interest? No
  • Comments Comments (
    0
    ) |
What type(s) of analysis is/are reported? Baseline biomarker level vs. outcomes
  • Comments Comments (
    0
    ) |
Continuous baseline measure
  • Comments Comments (
    0
    ) |
Study start date(s) 1996-1999
  • Comments Comments (
    0
    ) |
Male, percent 30.25
  • Comments Comments (
    0
    ) |
Race 100
  • Comments Comments (
    0
    ) |
not explicitly stated but study conducted in Japan
  • Comments Comments (
    0
    ) |
Dropouts, withdrawals, etc. nd
  • Comments Comments (
    0
    ) |
Baseline characteristics, continuous 61 (controls and cases
  • Comments Comments (
    0
    ) |
9 (controls) 8 (cases)
  • Comments Comments (
    0
    ) |
134.9 (controls and cases)
  • Comments Comments (
    0
    ) |
20.9 (controls) 21.4 (cases)
  • Comments Comments (
    0
    ) |
79.2 (controls) 78.9 (cases)
  • Comments Comments (
    0
    ) |
12.6 (controls and cases)
  • Comments Comments (
    0
    ) |
24.1 (controls) 24.0 (cases)
  • Comments Comments (
    0
    ) |
3.3 (controls) 3.2 (cases)
  • Comments Comments (
    0
    ) |
Baseline Diseases/Conditions 16.4 (controls) 16.3 (cases)
  • Comments Comments (
    0
    ) |
100
  • Comments Comments (
    0
    ) |
35.5 (controls) 35.8 (cases)
  • Comments Comments (
    0
    ) |
n3 Source Marine oil supplement
  • Comments Comments (
    0
    ) |




Results & Comparisons

No Results found.

Quality Dimensions
Dimension Value Notes Comments
Selection bias (NOT NESTED CASE CONTROL): Is there clear demonstration that the outcome of interest was not present at the start of the study (baseline)? Yes
  • Comments Comments (
    0
    ) |
Comparability/Adjustment (ALL OBSERVATIONAL STUDIES): Were the analyses adjusted for confounders (or other factors)? Yes including CVD risk factors and diet
  • Comments Comments (
    0
    ) |
Outcome assessment (ALL STUDIES): Were OUTCOME ASSESSORS adequately BLINDED? Unsure
  • Comments Comments (
    0
    ) |
Incomplete outcome data (attrition bias) due to amount, nature or handling of incomplete outcome data (ALL STUDIES) No
  • Comments Comments (
    0
    ) |
Nutrition, FFQ Baseline intake: Was the dietary assessment instrument (eg, FFQ) described to have measured n-3 FA (ALL STUDIES WITH FFQ)? Not Applicable
  • Comments Comments (
    0
    ) |
Nutrition, Baseline data: Were the ranges or distributions of the nutrient exposures adequately reported (ie, quantile means/medians SD and/or ranges) (ALL OBSERVATIONAL STUDIES)? Not Applicable
  • Comments Comments (
    0
    ) |
Additional Bias: Bias due to problems not covered elsewhere in the table. No
  • Comments Comments (
    0
    ) |
Do any specific outcomes have a high risk of bias (different than others)? If so, describe in Notes. No
  • Comments Comments (
    0
    ) |

Quality Rating
No quality rating data was found.