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Study Title and Description

Dietary fats and dietary cholesterol and risk of stroke in women.



Key Questions Addressed
2 Observational studies (longitudinal; quantile or continuous analysis)
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Primary Publication Information
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TitleData
Title Dietary fats and dietary cholesterol and risk of stroke in women.
Author Larsson SC., Virtamo J., Wolk A.
Country Division of Nutritional Epidemiology, National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. susanna.larsson@ki.se
Year 2012
Numbers Pubmed ID: 22265275

Secondary Publication Information
UI Title Author Country Year
α-Linolenic acid, linoleic acid and heart failure in women. Levitan EB., Wolk A., Håkansson N., Mittleman MA. Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, RPHB 230K, 1530 3rd Avenue S, Birmingham, AL 35294-0022, USA. elevitan@uab.edu 2012
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Fatty fish, marine omega-3 fatty acids and incidence of heart failure. Levitan EB., Wolk A., Mittleman MA. Department of Epidemiology, University of Alabama at Birmingham, School of Public Health, Birmingham, AL 39294, USA. elevitan@uab.edu 2010
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Extraction Form: Observational Studies
Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Observational: Prospective, longitudinal study of intake (eg, FFQ, biomarker)
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What is the name of this study? (e.g. DART, Physician's Health Study) Swedish Mammography Study
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Country in which study conducted (where subjects live) Sweden
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Funding source No industry relationship reported (funding or affiliations reported)
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Eligibility Criteria: All women in the Swedish population register born between 1914 and 1948 and living in Västmanland and Uppsala counties in central Sweden. only women who completed the 1997 questionnaire are included in this study. Participants who did not provide or provided incorrect national identification numbers, who reported implausible energy intakes (>3 standard deviations from the natural logarithm transformed mean), who had a previous diagnosis of cancer (other than nonmelanoma skin cancer) or HF were excluded. Only women with no baseline history of MI or diabetes were included.
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Study Population Primary Prevention, Healthy
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Conflict of interest No conflict of interest (explicitly stated)
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Does the study report a subgroup or predictor (regression) analysis for an outcome of interest? ... Which subgroups/predictors? Yes ... Baselin HTN
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What type(s) of analysis is/are reported? Baseline intake (eg, from FFQ) vs. outcomes
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Study start date(s) 1997
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Male, percent 0
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Race nd
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Dropouts, withdrawals, etc. 16803
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56,030
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30
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did not return 1997 questionnaire
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Baseline characteristics, continuous 62
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nd
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nd
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nd
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nd
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nd
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nd
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nd
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25
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Baseline Diseases/Conditions 0
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8
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History of high cholesterol
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20
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n3 Source Fish diet
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Results & Comparisons

No Results found.

Quality Dimensions
Dimension Value Notes Comments
Selection bias (NOT NESTED CASE CONTROL): Is there clear demonstration that the outcome of interest was not present at the start of the study (baseline)? Yes
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Comparability/Adjustment (ALL OBSERVATIONAL STUDIES): Were the analyses adjusted for confounders (or other factors)? Yes Including diet and CVD risk factors
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Outcome assessment (ALL STUDIES): Were OUTCOME ASSESSORS adequately BLINDED? LOW
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Incomplete outcome data (attrition bias) due to amount, nature or handling of incomplete outcome data (ALL STUDIES) LOW
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Nutrition, FFQ Baseline intake: Was the dietary assessment instrument (eg, FFQ) described to have measured n-3 FA (ALL STUDIES WITH FFQ)? Yes Measured n-3 FA from BOTH diet and supplements
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Nutrition, Baseline data: Were the ranges or distributions of the nutrient exposures adequately reported (ie, quantile means/medians SD and/or ranges) (ALL OBSERVATIONAL STUDIES)? No
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Additional Bias: Bias due to problems not covered elsewhere in the table.
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Do any specific outcomes have a high risk of bias (different than others)? If so, describe in Notes.
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Quality Rating
No quality rating data was found.