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Study Title and Description

Dietary fatty acids and the risk of hypertension in middle-aged and older women.



Key Questions Addressed
2 Observational studies (longitudinal; quantile or continuous analysis)
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Primary Publication Information
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TitleData
Title Dietary fatty acids and the risk of hypertension in middle-aged and older women.
Author Wang L., Manson JE., Forman JP., Gaziano JM., Buring JE., Sesso HD.
Country 900 Commonwealth Ave East, Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA. luwang@rics.bwh.harvard.edu
Year 2010
Numbers Pubmed ID: 20713915
6972 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Observational Studies
Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Observational: Prospective, longitudinal study of intake (eg, FFQ, biomarker)
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What is the name of this study? (e.g. DART, Physician's Health Study) Women's Health Study
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Country in which study conducted (where subjects live) US
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Funding source No industry relationship reported (funding or affiliations reported)
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Eligibility Criteria: female US health professionals, aged 39 years and free from cardiovascular disease and cancer (except nonmelanoma skin cancer). Excluded: women who had hypertension at baseline, defined as having a self-reported physician diagnosis of hypertension, self-reported current systolic BP 140 mm Hg or diastolic BP 90 mm Hg, or use of antihypertensive treatment, implausible total daily energy intake, incomplete FFQ, and prerandomization cardiovascular disease or cancer.
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Study Population Primary Prevention, Healthy
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Conflict of interest No Data regarding conflict of interest
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Does the study report a subgroup or predictor (regression) analysis for an outcome of interest? ... Which subgroups/predictors? Yes ... age
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What type(s) of analysis is/are reported? Baseline intake (eg, from FFQ) vs. outcomes
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Study start date(s) 1992
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Male, percent 0
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Race 95
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Dropouts, withdrawals, etc. 0
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28100
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0
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Baseline characteristics, continuous 54
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25
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Baseline Diseases/Conditions 1.25
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24.6
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history of hypercholesterolemia
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n3 Source Fish diet
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Results & Comparisons

No Results found.

Quality Dimensions
Dimension Value Notes Comments
Selection bias (NOT NESTED CASE CONTROL): Is there clear demonstration that the outcome of interest was not present at the start of the study (baseline)? Yes
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Comparability/Adjustment (ALL OBSERVATIONAL STUDIES): Were the analyses adjusted for confounders (or other factors)? Yes Including CVD risk factors, but not diet
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Outcome assessment (ALL STUDIES): Were OUTCOME ASSESSORS adequately BLINDED? HIGH self-report
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Incomplete outcome data (attrition bias) due to amount, nature or handling of incomplete outcome data (ALL STUDIES) LOW
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Nutrition, FFQ Baseline intake: Was the dietary assessment instrument (eg, FFQ) described to have measured n-3 FA (ALL STUDIES WITH FFQ)? Yes Measured n-3 FA from ONLY diet
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Nutrition, Baseline data: Were the ranges or distributions of the nutrient exposures adequately reported (ie, quantile means/medians SD and/or ranges) (ALL OBSERVATIONAL STUDIES)? No only medians given
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Additional Bias: Bias due to problems not covered elsewhere in the table.
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Do any specific outcomes have a high risk of bias (different than others)? If so, describe in Notes.
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Quality Rating
No quality rating data was found.