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Study Title and Description

Fish oil, selenium and mercury in relation to incidence of hypertension: a 20-year follow-up study.



Key Questions Addressed
2 Observational studies (longitudinal; quantile or continuous analysis)
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Primary Publication Information
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TitleData
Title Fish oil, selenium and mercury in relation to incidence of hypertension: a 20-year follow-up study.
Author Xun P., Hou N., Daviglus M., Liu K., Morris JS., Shikany JM., Sidney S., Jacobs DR., He K.
Country Department of Nutrition, Gillings School of Global Public Health and School of Medicine, North Carolina, Chapel Hill, NC 27599, USA.
Year 2011
Numbers Pubmed ID: 21205024
6978 (internal)

Secondary Publication Information
There are currently no secondary publications defined for this study.


Extraction Form: Observational Studies
Design Details
Question... Follow Up Answer Follow-up Answer
Study Design Observational: Prospective, longitudinal study of intake (eg, FFQ, biomarker)
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What is the name of this study? (e.g. DART, Physician's Health Study) Coronary Artery Risk Development in Young Adults (CARDIA)
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Country in which study conducted (where subjects live) US
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Funding source No industry relationship reported (funding or affiliations reported)
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Eligibility Criteria: age 18-30 in 1985,balanced by age (18–24 and 25–30), gender, ethnicity (AfricanAmerican and Caucasian), and education (high school or below and beyond high school). We excluded participants who reported implausible total energy intake (<800 or >8000 kcal/d for men, and <600 or >6000 kcal/d for women), participants with missing data on exposure variables at all diet assessments, and pregnant women at any examination.
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Study Population Primary Prevention, Healthy
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Conflict of interest No Data regarding conflict of interest
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What type(s) of analysis is/are reported? Baseline intake (eg, from FFQ) vs. outcomes
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Study start date(s) 1985
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Male, percent 46.9
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Race 50.6
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Dropouts, withdrawals, etc. 0
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4508
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0
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Baseline characteristics, continuous 24.9
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3.7
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110
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10.2
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68.3
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8.8
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24.4
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4.9
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n3 Source Fish diet
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Results & Comparisons

No Results found.

Quality Dimensions
Dimension Value Notes Comments
Selection bias (NOT NESTED CASE CONTROL): Is there clear demonstration that the outcome of interest was not present at the start of the study (baseline)? Yes
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Comparability/Adjustment (ALL OBSERVATIONAL STUDIES): Were the analyses adjusted for confounders (or other factors)? Yes Including diet and CVD risk factors
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Outcome assessment (ALL STUDIES): Were OUTCOME ASSESSORS adequately BLINDED? LOW
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Incomplete outcome data (attrition bias) due to amount, nature or handling of incomplete outcome data (ALL STUDIES) LOW
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Nutrition, FFQ Baseline intake: Was the dietary assessment instrument (eg, FFQ) described to have measured n-3 FA (ALL STUDIES WITH FFQ)? Yes Measured n-3 FA from ONLY diet
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Nutrition, Baseline data: Were the ranges or distributions of the nutrient exposures adequately reported (ie, quantile means/medians SD and/or ranges) (ALL OBSERVATIONAL STUDIES)? No
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Additional Bias: Bias due to problems not covered elsewhere in the table.
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Do any specific outcomes have a high risk of bias (different than others)? If so, describe in Notes.
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Quality Rating
No quality rating data was found.